An experimental dissertation on the chemical and medical properties of the nicotiana tabacum of Linnaeus, commonly known by the name of tobacco / By Edward Brailsford.
- Brailsford, Edward, -1856
- Date:
- 1799
Licence: Public Domain Mark
Credit: An experimental dissertation on the chemical and medical properties of the nicotiana tabacum of Linnaeus, commonly known by the name of tobacco / By Edward Brailsford. Source: Wellcome Collection.
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![i Sa EX PEO R TIM BUN © 97, I gave to a large dog, thirty grains of the extract, confifting of the gum and refin, which produced no {fenfi- ble effects for the firft hour; in an hour and fifteen mi- nutes, he difcovered fome commotion in the ftomach, by the faliva which run from the mouth, and alfo by feveral convulfions of the body, as if inclined for vomiting. No- thing was ejected from the ftomach, but the dog had co- pious and repeated difcharges through the medium of the rectum, for feveral hours after. The enfuing day he had perfectly recovered, and fuftained no apparent inconveni- ence from his bolus. Ex PERIMENT. 28, Fifteen grains of the refin were given to a dog of the fame f{trength, which caufed an inclination to vomit in the of camphor, and as the analogy is fo great, I will give the extrac& from the Londen medical obfervations, as related by Mr. Hoffman. ¢ T gave,’’ fays Mr. Hoffman, “ toa large grey hound, two drachmas of camphor, in a ball of hogs lard. Three quarters of an hour after, the dog began to look wild and furious, lolled ont his tongue, work-— ed in his flanks, as ifexceflively fatigued. [found the nervous parts fo violently contracted, their rigidity fo great, and the dog when at- tempting to walk, inftead of advancing, recoiled backwards, drag- ging his forelegs after him, as if he dreaded by going forwards, to fali down a precipice. He then fel] into convulfions. After alittle time he got up, began to walk, ftriking his head againf{ any thing, that happened in his way; tumbling and tottering as if intoxicated. When I offered him fome water to drink, notwithfanding he appear— ‘ed very thirfty, he refufed it. The fymptoms refembied the Aydropho— £iz. In ahout twenty-four hours every appearance of madnefs, gra+ dually fubfided, and left the dog ina quite weak and feeble condi- tion; but afterwards he recovered gradually,](https://iiif.wellcomecollection.org/image/b32885945_0059.jp2/full/800%2C/0/default.jpg)


