Cancer of the uterus : its pathology, symptomatology, diagnosis, and treatment : also the pathology of diseases of the endometrium / by Thomas Stephen Cullen ; with eleven lithographic plates and over three hundred coloured and black illustrations in the text by May Brödel and Hermann Becker.

  • Thomas Stephen Cullen
Date:
1900
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Licence: Public Domain Mark

Credit: Cancer of the uterus : its pathology, symptomatology, diagnosis, and treatment : also the pathology of diseases of the endometrium / by Thomas Stephen Cullen ; with eleven lithographic plates and over three hundred coloured and black illustrations in the text by May Brödel and Hermann Becker. Source: Wellcome Collection.

Provider: This material has been provided by the Francis A. Countway Library of Medicine, through the Medical Heritage Library. The original may be consulted at the Francis A. Countway Library of Medicine, Harvard Medical School.

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    CHAPTEE I INTRODUCTORY 1. Historical sketch. 2. Frequency of carcinoma of the uterus. 3. Sources of our material. 4. Varieties of carcinoma of the uterus. Although carcinoma was described by pathologists early in the present cen- tury, its epithelial origin was not definitely established. Eobin* was probably one of the first to demonstrate that the morbid process had its commencement in the epithelium. In an article on Some Gland Hypertrophies, published in 1852, in speaking of certain tumours of the cervix, he says: There is an infil- tration of the tissue by epithelium. The elements of the tissue atrophy, and where there is friability of the diseased structures the epithelium is more abun- dant than the other elements. When ulceration commences there is rapid pro- liferation of the tissue. The ulceration is foetid. It is important to operate early. Cornil, f in 1865, in his Contributions to the History of the Histological Development of Epithelial Tumours, also showed clearly the epithelial origin of squamous-cell carcinoma. In speaking of a tumour of the breast, he says : This anatomical protocol which we have submitted to the control of the members of the Biological Society, and especially to M. Eobin, shows absolutely that the mammary tumour, which we call scirrhus, consists primarily in an increased production of the gland epithelium. In 1865 Thiersch X published his valuable monograph on epithelioma of the skin. But although Eobin, Cornil, and Thiersch showed that epitheliomata were derivatives of the squamous epithelium, the starting-point of other carcinomata as yet remained unsettled, many authorities still believing that they were of con- * Robin. Sur quelques hypertrophies glandulaires. Gaz. d. hop., Paris, 1852, t. xxv, p. 41. f Cornil, Victor. Contributions a Vhistoire du developpement histologique des tumeurs epithe- liales, 31 pp., 4 pi., 8vo, Paris [1865]. X Thiersch, C. Der EpitheJialkrebs, namentlich der Emit. Eine anatomisch-khnische Unter- suehung. Mit einem Atlas mikroskojnscher Abbildungen, xvi, 310 pp., 8vo; Atlas, 11 1., 11 Taf., 4to, Leipzig, 1865.