On inflammation / by G. Thin.

  • Thin, George, -1903.
Date:
[1876?]
Catalogue details

Licence: Public Domain Mark

Credit: On inflammation / by G. Thin. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    single, at oLlior times accumulated in gi-oups, wliicli are arranpod in two directions wliicli cross eacli other at a right angle. Again/ describing-a cornea in which inflammation had lieeu ]iroduced indirectly by a thread passed through tlie bulb, the cornea being excised and treated on the second day by chloride of gold, the same observers remark, We find on the periphery of the cornea, a part equal in extent to the whole field, in which there is nothing but spindle elements, which are arranged in two directions at right angles to each other. The protoplasm of these cells is relatively scant, and they contain invariably two or three rounded nuclei. Klihne is cited by Strieker ^ as having seen on the border of a frog's cornea, which he had mechanically irritated, stellate cor- puscles become spindle-shaped. Eecklinghausen ^ states that in the inflamed cornea he found two kinds of cells, which he did not find in the healthy cornea, namely, migrating cells, larger, and moving more slowly thau similar cells which are seen in the healthy cornea, and sj)indle-shaped cells having fewer processes than the fixed cells, sometimes rounded at at one end and having a process at the other. These, he suggests, may be a transition form of fixed cells which are becoming movable. Hansen * states that in the inflamed cornea he saw transition forms, from undoubted cornea-corpuscles to elongated perfectly spindle-shaped structures, which are to be considered as having reached the extreme degree of change of form. He also fre- quently found parts of the cornea where there was not a single normal cornea-corpuscle remaining, the whole field being filled with small oblong bodies crossing each other. He suggests as a possible cause of this supposed change of form, that the cor- puscles are acted on by a'stream which, passing through the cornea, washes them into the interfibrillary spaces, whose arrange- ment in parallel and crossing layers they accordingly assume. Bottcher,* instead of nitrate of silver, used cldoride of zinc, and when he cauterized a limited point in the centre of a frog's cornea by this irritant, he succeeded in producing inflammatory changes, which were independent of any change that proceeded from the conjunctiA'^al vessels next the corneal border. As part of the process by which these changes were produced, he beheves tliat in three days all the stellate cells had been transformed into spindle cells. 1 Log. cit., p. 11; ^ Hiuulbuch, p. 14. Eitevuiiir, etc., Vircliow's Arcliiv, Bd. 28, ]). 180. Wien. Med. Jalnb., 1871. ' Vircliow's Avclii\-.