Clinical diagnosis : the bacteriological, chemical, and microscopical evidence of disease / by Rudolf v. Jaksch ; translated from the second German edition by James Cagney ; with an appendix by Wm. Stirling.

  • Cagney James.
Date:
1890
Catalogue details

Licence: Public Domain Mark

Credit: Clinical diagnosis : the bacteriological, chemical, and microscopical evidence of disease / by Rudolf v. Jaksch ; translated from the second German edition by James Cagney ; with an appendix by Wm. Stirling. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

    34/432 (page 6)
    posed to bo most tibuiidfintly present in the blood of persons suffer- ing from chronic diseases) and are said to increase in number durinsj pregnancy (^Halla), in conditions of regeneration (Afanassiew'), in febrile anaemia (Fusari), find to diminish in fever.^’^] Ihe physiology of the red and white blood-corpuscles is sufficiently set forth in the Text-books of that science.i*^ Pathologically, the corpuscles exhibit changes aus to quantity and character which are of the utmost importance in diagnosis. Tliese changes seldom occur separately, but are usually combined,—although alterations of the structure of the corpuscles may be more pronounced in some cases, of their number in others. We shall consider :— 1. The diminution in the number of the cellular elements of the blood {oligocythsemia). 2. The increase in the number of the cellular constituents. An absolute increase of this kind has not j’et been proved to occur, but a relative preponderance of white corpuscles is often met with. This happens normally during digestion {^physiological lencocytosis),—as a transient phenomenon in a number of morbid states (pathological lencocytosis), and as a persistent condition (leuheemia). 3. Changes in the form of the blood-corpuscles (poilcilocytosis, mikro- cythsemia). 1. OUgfOCythaBmia.— Vierordt has comj3uted that in health the number of red blood-corpuscles is five millions in a man, and millions in a woman to the cubic millimetre of blood.^® In di.sea.se the number may diminish temjjorarily or permanently to two millions, or even sink as low as 360,000 per cubic millimetre. Such a condi- Fiq. I.—Blood-Plates from Normal Blond.