Volume 1

Manual of pathological histology / by Cornil and Ranvier.

  • Victor André Cornil
Date:
1882-1886
Catalogue details

Licence: Public Domain Mark

Credit: Manual of pathological histology / by Cornil and Ranvier. Source: Wellcome Collection.

    30/672 page 12
    tissue. We thought then that this tissue was formed of a funda- mental fibrillar substance, in the midst of which canals were hollowed out (plasmatic canals, serous channels) and that the plas- matic or connective-tissue cells were included within these canals. This false interpretation arose from the fact that connective tissue was generally examined in transverse sections after desiccation or hardening in chromic acid or alcohol, and after the action of acetic acid. But Henle, who, in studying connective tissue, continued to have recourse to dissociation, always declared himself against the teaching of Virchow and his pupils. His description of con- nective-tissue bundles is perfect. He recognised their fibrillar structure, and described the annular and spiral fibres which are twisted round the fasciculi, lacing them together and consolidating them. Henle, however, was not aware of the existence of active cells, so that, according to him, connective tissue only contained Fig. 8.—Connective Tissue. a, connective-tissue bundles cut 'transversely or obliquely to their direction ; b, connective-tissue cells. Magnified 200 diameters. Section obtained after desiccation, stained with carmine and treated with acetic acid. elements derived from primitive cells, and which he called fibres of nuclei (annular, spiral, and elastic fibres). Annular and spiral fibres are stained red with carmine, and retain their colour after the addition of acetic or formic acid, whilst elastic fibres remain colourless. The nuclei of connective-tissue cells, and the surface of the bundles, are stained with carmine exactly as the spiral fibres. Virchow, who recognised the existence of the nuclei, considered that they were contained within cells analogous to osseous corpuscles, in that they are necessarily limited by the surface of the fasciculi, which are also distinguished by their colour. Although Virchow was mistaken in the form, the relations, and the signification of the connective-tissue cells, yet to him never- theless is due the merit of having affirmed their existence. To understand the structure of connective tissue, that is to
    No text description is available for this image
    No text description is available for this image
    No text description is available for this image