"A footnote on allostery"

Date:
1965-1966
Reference:
PP/CRI/H/3/19/1
Catalogue details

Licence: In copyright

Credit: "A footnote on allostery". Source: Wellcome Collection.

    21/117
    (1) For a given value of t , but differing values of e, is always a maximum when c « 0. Por these conditions (i.e. o=0) n f max is given by where a (the value of a which makes n* a maximum) is that max value of a which satisfies the equation _ (1 + a) n 1 £(n - 1) a - l] » L (2) Por a given value of c (c=^ 0) but differing values of Í , n ' m ax i3 a maximum when ^ 2 ° 58 and occurs wjaen 1 max » -f = j-L . This is the condition that makes the binding 13 formula n . n . - 4 (Jn - 1) = 4jÖ (n - 1) n max - (1 + e )2 (1 + fc)2 Equivalent formulae are n 'max ~ 1 3 U ~ D lj = (n - 1) ^ + ^ As c —0 (and thus f ——«3> oô ) n 1 ——^ n. It is worth pointing out that when f^c ^ 1 the value of n' at the special value of « which makes p s 1 is given by ... > (n - 1) 2 (1 + n. ■, —(i + I )(i + to) P 1
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