The human female ovary, with reference to corpora lutea, both true and false / by Frank Renaud.
- Renaud, F. (Frank), 1819-1904.
- Date:
- [1845]
Licence: Public Domain Mark
Credit: The human female ovary, with reference to corpora lutea, both true and false / by Frank Renaud. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
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![ed, whilst in others they either do not exist, or are obscured by the aggregation of the granules surround- ing them.i This demonstration puts a period to speculations as to the yellow matter being altered blood, or intumescence of the vascular membrane of the Graafian follicle. Further- more, as the body is distinctly formed of cells, it follows, that it is a substance sui generis—a consequence of some action or actions excited in the ovary in order to its production. To inves- tigate the mode of production of these cells, it appears most consonant with the physiology of generation to consider the changes wrought in the ovum, prior to the advent of those actions which first cause the corpus luteum to be deve- loped. The yolk globule is originally produced from granular matters secreted by the vascular ovisac. In some instances, as in the umbilical vesicle of the embryo lizard, the most accustomed eye can de- 1 tect little or no difference between it and the cells of false yellow ^ bodies. If a fully developed ovum be placed in the field of a good J microscope, the granular matter is found to be mixed up with cells, \ perhaps more regular in form, and much smaller, yet not essen- tially differing from either of the foregoing. If, then, these appear- i ances be traceable in the unruptured follicle, it seems to follow, that, 1 as the entire follicle is comparable to a compound cell, the fluids within it must directly or indirectly emanate from actions taking j place on the inner surface of the cell wall, i. e. the vascular mem- ' brane of the Graafian follicle. Hence, it appears a legitimate conclu- ] sion, that the yellow matter of the false corpus luteum has its origin here also. This mode of stating the case has been observed by reason of contradictory statements having recently been published regarding the exact locality of this yellow matter—Bischoff espous- ing Baer’s doctrine as to the secretion being found on the inner surface of the inner membrane of the follicle, whilst Dr Montgo- mery and others have asserted it to be found on the inner surface of the external membrane, and between the two. The following case is cited at full, to show that the yellow matter may be found lying free in the cavity of the spurious body,—an instance of depar- ture from a general rule, rather than an illustration of the rule itself. Isabella Smith, aged 36, took a poisonous dose of opium on the .25th May 1844. She partially recovered, but relapsed, and died on the 28th, at which time the catamenia were upon her. The os uteri is dilated and elongated laterally—the walls are hypertrophi- 1 Much similarity of form and constituent principles will be observable between these cells, and the exudation corpuscle, characteristic of inflammation:—for some good illustrations of which, vide “ Inflammation of Nervous Centres,” by Dr John Hughes Bennett, in the Edinburgh Med. and Surg. Journ. for 1843. Fig. 1](https://iiif.wellcomecollection.org/image/b22376562_0008.jp2/full/800%2C/0/default.jpg)
