The biochemical genetics of man / edited by D. J. H. Brock, O. Mayo.

Date:
1978
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: The biochemical genetics of man / edited by D. J. H. Brock, O. Mayo. Source: Wellcome Collection.

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    The first edition of this outstanding treatment of human genetics has, since its publication in 1972, established for itself a permanent niche in many university biochemistry and genetics courses as the standard reference work in the field. It was then regarded as a pioneer study, attempting a comprehensive treatment of both theory and fact, and balancing detail with an understanding of underlying principle. This second edition follows, to a large extent, the format and content of the first. However, the editors have been concerned not only to incor¬ porate recent findings wherever possible, but more particularly to strengthen the chapters dealing with principles, thus adding to the book's reference value. The book deals with both the more conventional subjects of biochemical genetics, such as inborn errors of metabolism and protein polymorphism, and other aspects of the molecular variation of man, such as blood groups, leucocyte antigens, haemoglobin diseases, immunoglobinopathies and disorders of coagulation. The role of polymorphism in evolution, and future direc¬ tions in as yet unsolved Mendelian diseases, are also treated. These topics are covered com¬ prehensively and at various points related back to the first three chapters in which the molecular basis of variation is fully discussed. This second edition will be an invaluable source of reference for researchers and students in human genetics, while paediatricians, haematol- ogists, immunologists, biochemists and other medical workers with an interest in genetics will also find it useful. From reviews of the first edition 'It can be confidently recommended as a useful starting point for anyone wishing to enquire into a topic in human biochemical genetics or to gain a lead to basic information appertaining to a metabolic disorder with a significant genetic factor. ' D.A. Price-Evans in Heredity 'This volume provides a more comprehensive framework for human biochemical genetics than has been available previously . . . investigators in this and related fields will find the volume an important reference and guide to further reading. ' Leon E. Rosenberg in Science
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