Volume 2
Reports of the Sleeping Sickness Commission of the Royal Society.
- Royal Society (Great Britain). Sleeping Sickness Commission
- Date:
- 1903-19
Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
Credit: Reports of the Sleeping Sickness Commission of the Royal Society. Source: Wellcome Collection.
Provider: This material has been provided by Royal College of Physicians, London. The original may be consulted at Royal College of Physicians, London.
17/84 page 9
![4. ADULT FORMS AND DEVELOPMENTAL FORMS OF THE TRYPANOSOME FOUND IN SLEEPING SICKNESS. By ALBO CASTELLANI, M.D. (Florence), (Professor of Pathology and Bacteriology, Colombo INIedical College). [Eeceived July 21, 1903.] [With 2 Plates.] In previous publications of mine* I stated that in Sleeping Sickness patients I found, in twenty cases out of thirty-four, a trypanosome,. which I considered the cause of the disease. My results have been since then amply confirmed by such an authority on trypanosomes as Colonel Bruce. In this note I propose to give some details on the- morphology of the adult parasites and their developmental forms. Appearances of the Adult Tnjpanosome. Fresh Preparations.—The parasite has the usual general outline of the other trypanosomes. It has a worm-like shape, and one observes in it one end terminating Avith a flagellum, the other more or less Ijluntly conical, though sometimes it may be quite pointed, an imdulating membrane and a vacuole. The protoplasm does not appear to have quite a uniform structure, but rather an alveolar one, as described by Phmmer and Bradford in Tryp. Brucci, although apparently far from being so well marked. At first the parasite moves fairly actively, but, on observing the preparation for some time with the microscope, one sees that the movements by-and-by become more sluggish, until they stop altogether. Frequently the trypanosome stops near a leucocj^te, which by degrees engulfs it. In other instances, after having slowed down very much in their movements, the parasites stop far from any leucocytes and disappear suddenly as if they had been dissolved by the liquid. 0)i](https://iiif.wellcomecollection.org/image/b24750530_0002_0017.jp2/full/800%2C/0/default.jpg)
