Selected monographs.

  • New Sydenham Society
Date:
1888
Catalogue details

Licence: Public Domain Mark

Credit: Selected monographs. Source: Wellcome Collection.

Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)

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    30th the atmospheric pressure increases, but the min. temp, is still lower. It is therefore probable that cooling of the air and increase of its humidity had influenced the production of the strong febrile accesses in the infected, and had determined a fall of temp, in the non-infected animals. Autopsy, No. IV.—Well nourished; had gained W. 63 gr. since April 26th. Spleen greatly enlarged (Table I., fig. 4); L. 67'3 mm.; B. 13 mm.; T. 4*3 mm.; I. S. 2,460, i.e., four times the normal, contracted, capsule wrinkled, and poor in blood. Liver and kidneys congested, but normal. Mesenteric glands enlarged, whitish, rich in lymph. Patches of Peyer slightly elevated, and greyish white. Intestinal mucous mem- brane slightly reddened. Uterus large, placental insertion faint, mucous membrane smooth, reddish. Lungs large, subpleural ecchymoses. Heart contracted. Abdominal veins contain much fluid blood. In the lymph many oval shining corpuscles with active movement; a few also in the spleen. Cultivations were made with blood collected in capillary tubes. In one bacillus development took place. In the spleen were many large cells containing fragments of red globules and many shining granules ; much brown and a considerable quantity of black pigment in this spleen, which pigment was stained blue by ferrocyanide of potassium and hydrochloric acid. C. Parallel experiments on the efficacy of fluid obtained by cultivation in urine of, samples of air collected in Ninfa and Fogliano.—These had for their object to discover if any difference- existed between the action of the cultivation fluid before and! after filtration. The cultivation fluid, by means of which the malarious infec- tion had already been produced in No. II., was filtered through a cell of plaster of Paris by means of a Bunsen's pump. Sixteen cc. of filtered fluid were injected, May 2nd, by several punctures under the skin of the back of No. III., which had since April 29th onwards had a normal temperature, and from previous researches might be supposed to have a predisposition to resist malarious infection. Into No. V., not used in any previous experiment, was injected only 3'2 cc. of the liquid remaining in the filter.