On the changes observed in healthy medium-sized arteries and in tendon ligatures during the first four weeks after ligation / by Sheridan Delépine and C.T. Dent.

  • Auguste Sheridan Delépine
Date:
1891
Catalogue details

Licence: Public Domain Mark

Credit: On the changes observed in healthy medium-sized arteries and in tendon ligatures during the first four weeks after ligation / by Sheridan Delépine and C.T. Dent. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

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    Seventeenth Day's Specimen. General remarks.—In this specimen, as in the ninth specimen, there are very marked inflammatory changes. The occlusion is perfect (Fig. 4). 1. Contents. Both the proximal and the distal portions of the artery are occupied by vascular young connective tissue. Groups of decolorised red blood-corpuscles can be recognised in the proximal plug, which is evidently taking the place of the original clot, which has now almost entirely disappeared. The proximal plug is composed, as in the last case,— 1st. Of a non-vascular layer of flattened cells lining the free concave surface of the plug, and continuous with the endothelium of the thickened intima. 2nd. Of a deeper part occupying the rest of the proximal cul-de-sac, and composed of bands or ramifying tracts of spindle or branched cells. Most of these tracts are young vessels and have a distinct lumen, bnt as yet contain no blood. Between these tracts small clumps of decolorised and very indistinct red blood-corpuscles and also granules of pig- ment are found. These are the only remains of the original blood-clot. In the distal plug (which in this case is larger than in any other case) the thickened tunica intima is continuous, as in the proximal plug, with the new connective tissue. This connective tissue presents the arrangement described above; the young vessels do not, however, present so distinct a lumen, and the tracts of cells are separated by a hyaline material which contains neither red blood- corpuscles nor blood-pigment. Although the free superficial layers of both plugs are non-vascular, generally speaking, a few pretty large vessels extend through them in or near the axis of the vessel. The meaning of this arrangement will be clear
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