On the escape of the heart from vagus inhibition.

  • Theodore Hough
Date:
1895
Catalogue details

Licence: Public Domain Mark

Credit: On the escape of the heart from vagus inhibition. Source: Wellcome Collection.

Provider: This material has been provided by the Augustus C. Long Health Sciences Library at Columbia University and Columbia University Libraries/Information Services, through the Medical Heritage Library. The original may be consulted at the the Augustus C. Long Health Sciences Library at Columbia University and Columbia University.

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    [Fro7n the Journal of Physiology. Vol. XVIII. No. 3, 1895.] ON THE ESCAPE OF THE HEART FROM VAGUS INHIBITION. By THEODORE HOUGH, Ph.D. (Four Figures in Text.) {From the Biological Laboratory, Johns Hopkins University of Baltimore, U. S. A.) Contents. Section 1. Introductory. The escape of the heart from vagus in- hibition is not the result of exhaustion of the fibres of the vagus nerve. Section 2. The efficiency of inhibition varies inversely with the vigour of the heart. Section 3. Technique of experiments. Description of the typical curves of escape for the terrapin, dog, rabbit, and cat. Section 4. The heart escapes, no matter how slight the initial slowing. Section 5. Rapidity of recovery by the inhibitory mechanism of the power to produce stand-still. Section 6. Relation between the strength of stimulus and the curve of escape. Section 7. On alternate stimulation of the vagi. Section 8. Summary. 1. Introductory. The Escape of the Heart from Vagus Inhibition is not the Result of the Exhaustion of the Fibres of the Vagus Nerve. Why does stimulation of the vagus nerve fail to keep the heart of a mammal at stand-still ? This question has been frequently asked and has received various answers. It was formerly supposed that the fibres of the vagus are in some respect different from other nerve fibres in that they are more easily exhausted by stimulation; this exhaustion has, moreover, been attributed either to the continued conduction of nervous impulses to the end organ or to a loss of irritability at the PH. XVIII. 11