Dental anaesthetics, a text-book for students and practitioners / With a contribution on analgesia, by John Bolam ... By Wilfred E. Alderson.

  • Alderson, Wilfred E.
Date:
1912
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Licence: In copyright

Credit: Dental anaesthetics, a text-book for students and practitioners / With a contribution on analgesia, by John Bolam ... By Wilfred E. Alderson. Source: Wellcome Collection.

Provider: This material has been provided by The University of Leeds Library. The original may be consulted at The University of Leeds Library.

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    and its toxicity is rated as one-third that of cocaine. It is said to have a toxic action on the heart. The dose is ^ to i gr.. and | to i per cent solutions may be used, though some writers recommend as high as 3 to 4 per cent. The analgesia obtained is very powerful. Acoin, Ansesthesine, Holocaine Hydro- chloride, and Nirvanin have also found a place in the long list of local analgesics, but proved unsuitability for the purpose, or want of sufficient experimental data, debars them from further mention at the present time, though it may be said of nirvanin that a future is predicted for it by American writers. It is freely soluble to form neutral solutions possessing germicidal properties, and has an estimated toxicity one-tenth that of cocaine, as much as 7 gr. having been injected at one time without complications. Analgesics can be obtained :— 1. In liquid form, either {a) in bottles, or {b) in sealed sterilized glass ampoules each containing a known quantity of solution of standard percentage strength. 2. In solid form, for solution in water. Of these i [b] and 2 are recommended. ANALGESIC MIXTURES. Of the numerous substances which have