Opera minora : a collection of essays, articles, lectures and addresses from 1866 to 1882 inclusive / by Edward C. Seguin.
- Edward Constant Seguin
- Date:
- 1884
Licence: Public Domain Mark
Credit: Opera minora : a collection of essays, articles, lectures and addresses from 1866 to 1882 inclusive / by Edward C. Seguin. Source: Wellcome Collection.
Provider: This material has been provided by the Francis A. Countway Library of Medicine, through the Medical Heritage Library. The original may be consulted at the Francis A. Countway Library of Medicine, Harvard Medical School.
643/708 page 629
![ON A PECULIAR CUTANEOUS LESION (ULCUS ELE- VATUM) OCCURRING DURING THE USE OF BRO- MIDE OF POTASSIUM.* In the last few years, more especially since tHe publication of Trousseau's lecture entitled Exanthèmes sudoraux,''^ t much atten- tion has been paid to toxic or medicamentous eruptions. Among these, the cutaneoiis lesions produced by the various bromides, when taken internally, have been particularly well studied, and quite a variety of eruptions have been observed and recorded by dermatologists and neurologists. In the last edition of Prof. Duhring's excellent work X we find a section devoted to this subject, and the following bromic erup- tions are described under the head of dermatitis medicamentosa. 1. Acne-form pustules. 2. Brownish discoloration of the skin. 3. Simple papular eruption. 4. Confluent or moUuscoid acne. 5. Maculo-papules. 6. Carbuncular acne. 7. Bullœ. 8. Rupia. Ulcers are not named in this list, and I do not know that they have ever been described, unless it be in the shape of isolated, ulcerated, carbuncular acne.* It has been my fortune to observe this year two cases of large, elevated ulcers upon the legs, occurring in epileptic patients using the bromide treatment, and I desire to place on record this new form of cutaneous lesion, probably medicamentous in origin. * From the Archives of Medicine, Oct., 1883. f Clinique médicale de l'Jffoteî-Dieu, 2me éd., 1865, i, p. 199. i Practical Treatise op Diseases of the Skin, 3d éd., Phila., 1882, p. 348, * Dr. A. Voisin, in his monograph, De l'Emploi de Bromure de Potassium dans les maladies Nerveuses, Paris, 187ô, mentions a very similar lesion, which undoubtedly Dr. Seguin had overlooked.—[R. W. A.]](https://iiif.wellcomecollection.org/image/b21077435_0643.jp2/full/800%2C/0/default.jpg)
