Embryology, with the physiology of generation / trans. from the German, with notes, by William Baly.
- Johannes Peter Müller
- Date:
- 1848
Licence: Public Domain Mark
Credit: Embryology, with the physiology of generation / trans. from the German, with notes, by William Baly. Source: Wellcome Collection.
Provider: This material has been provided by The University of Leeds Library. The original may be consulted at The University of Leeds Library.
370/392 page 130
![the blood from the left ventricle of the heart, from the umbilical artery arid vena cava superior, was composed principally of ordinary red non-nu- cleated corpuscles, with a very few pale granular cells, that from the liver and that also—though from this source the characters of the blood were less manifest—from the vena cava inferior just previous to its entrance into the right auricle, contained, besides red non-nucleated corpuscles, a considerable number of ordinary pale corpuscles like lymph-corpuscles, and several larger pale granular corpuscles, with distinct large nuclei. The appearances, indeed, presented by the blood obtained from these two latter sources, but especially from the liver, were just such as would indi- cate the existence of a process of rapid development of blood-corpuscles. Of this process the several varieties of corpuscles found, probably repre- sented so many stages from the first condition of pale spherical granular nucleated cells, to the coloured, flattened, smooth, non-nucleated corpuscles.* With regard to the probable mode in which the liver performs this office of developing blood-corpuscles, Kolliker does not offer any decided opinion. He considers that it bears no particular relation to the develop- ment of the proper secreting tissue of the organ, for the formation of blood-corpuscles in the liver takes place even before the secretion of bile commences. Professor E. H. Weber,] who also admits the importance of the liver as an organ for the formation of blood in the embryo, at least of birds and frogs, is of opinion that the elements of bile and the corpuscles of blood stand, as it were, in a kind of complemental relation to each other, the separation of the one furnishing the conditions favourable to the development of the other. The seat of formation, however, both of the blood corpuscles and the bile is considered by Weber to be in the net- work of minute biliary ducts, and not in the blood-vessels. Certain ma- terials (the contents of the yolkTsac in early embryonic life) are abstracted from the latter into the former set of vessels; and from these materials are formed the elements of bile, and the corpuscles of blood : the one are conveyed through the bile ducts to the gall-bladder and intestines, the others make their way into the blood-vessels; but in what manner is by no means clear. Whatever share may be taken by the liver in the production of blood- corpuscles during embryonic life, the results of the most recent observa- tions on the subject of the development of the blood, especially of those furnished by Kolliker,]; Mr. Wharton J ones, § and Fahrner,|| to the general truth of which the testimony of the writer, from observations above alluded to, may be added, have shewn that, in the blood of the early Mamma- lian embryo, at least three several kinds of corpuscles are met with. * And, since the above was written, still further confirmation of the truth of such an opinion has been obtained from additional examinations of the blood of other Mammalian embryos at different ages. t Henle und Pfeufer's Zeitschrift, 1. c. p. 161. + Op. cit. § Philosophical Transactions, 1846. || Op. cit.](https://iiif.wellcomecollection.org/image/b21522145_0370.jp2/full/800%2C/0/default.jpg)
