A note on the histology of a case of myelomatosis (multiple myeloma) with Bence-Jones protein in the urine (myelopathic albumosuria) / by F. Parkes Weber and J.C.G. Ledingham.

  • Frederick Parkes Weber
Date:
1909
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Licence: In copyright

Credit: A note on the histology of a case of myelomatosis (multiple myeloma) with Bence-Jones protein in the urine (myelopathic albumosuria) / by F. Parkes Weber and J.C.G. Ledingham. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    Wright observed that plasma-cells occur in the normal bone-marrow, and we now know that they may occur in all organs. Myeloid transformations may sometimes, as already stated, occur in the spleen, lymphatic glands and liver. Hence, as Lubarsch remarks, the occur- rence of “metastatic” nodules consisting of myelocyte-like cells or plasma- cells would readily fit in with the conception of myeloma as a systemic affection. At present, however, the time is not ripe for the adoption of very dogmatic views as to the exact place of myeloma in the classification of diffuse affections involving the haematopoietic apparatus. REFERENCES. Abrikossoff, A. J. Virchoiv's Archiv, Berl., 1903, clxxiii, p. 335. Aschoff, L. Aerztlicher Verein zu Marburg, December 20, 1905. Report in Munch, vied Wochenschr., liii, 1906, p. 337. (The same case has been described hy Gluzinski and Reichenstein, “Myeloma und Leuceemia lymphatica plasmacellularis,” Wien. klin. Wochenschr., 1906, xix, p. 336. Benda. “Verein f. inn. Med.,” Berl., November 2, 1908, report in Berl. klin. Wochenschr., 1908, xlv, p. 2042. Charles and Sanguinetti. Brit. Med. Jowm., 1907, i, 196. Christian, H. A. Journ. of Exp. Med., New York, 1907, ix, p. 325. Decastello, A. von. Verhandl. des Kong. f. inn. Med., Wiesb., 1908, xxv, p. 620. Herz, A. Wien. vied. Wochenschr., 1908, lviii, pp. 1289, 1360. Hoffmann, R. Beitr. z. Path. Anat. u. z. allg. Path., Jena, 1903, xxxv, p. 317. Hueter. (Aerztlicher Verein in Hamburg, Biolog. Abteilung, February 12, 1907.) Munch, vied. Wochenschr., 1907, liv, p. 811. Jellinek, S. Virchow’s Arcliiv, 1904, clxxvii, p. 96. Lubarsch, O. Virchoiv's Archiv, 1906, clxxxiv, p. 213. MacCallum, W. G. Journ. of Exp. Med., New York, 1905, vi, p. 53. Menne, E. Virchow’s Archiv, 1906, clxxxiii, p. 115. Occhi, C. degli. Brit. Med. Journ., 1907, ii, Epitome No. 138, p. 41. Permin, C. H. Virchow's Archiv, 1907, clxxxix, p. 439. (A bibliography up to 1907 is included by Permin.) Ribbert, H. Centralbl. f. allg. Path. u. Path. Anat., Jena, 1904, xv, p. 237. Saltykow, S. Virchow’s Archiv, 1903, clxxiii, p. 531. Scheele and Herzheimer. Zeitschr. f. klin. Med., Berl., 1904, liv, p. 57. Simmonds. (Aerztlicher Verein in Hamburg, Biolog. Abteilung, April 10, 1906.) Milnch. vied. Wochenschr., 1906, liv, p. 1438. Sternberg, C. Verhandl. d. deutsch. path. Gesellsch., 6te Tagung, September, 1903, Jena, 1904, p. 34. Tschistovitsch and Kolesnikowa. Buss. Wratsch., 1908, Nos. 39-40; abstract in Folia Haeinatologica, Berl., 1909, vii, p. 150. Umber. (Aerztlicher Verein in Hamburg, Biolog. Abtoilung, March 3, 1908.) Milnch. vied. Wochenschr., 1908, lv, p. 587. Verebely, T. von. Beitr. z. klin. Chir., Tubingen, 1906, xlviii, p. 614. Weber, F. P. Med.-Chir. Trans., Lond., 1903, lxxxvi, p. 395. Wright, J. H. Johns Hopkins Hosp. Bep., Balt., 1900, ix, p. 359.
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