A guide to the examination of the urine in health and disease, for the use of students / by Alfred Markwick.

Date:
1847
Catalogue details

Licence: Public Domain Mark

Credit: A guide to the examination of the urine in health and disease, for the use of students / by Alfred Markwick. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    of uroxanthin. This is constantly noticed in Bright’s disease on treating urine abounding in uroxanthin with an acid, and allowing it to stand for a couple of days ; uroglaucin separates in dark blue crystal- line groups, visible to the naked eye, partly on the surface and partly at the bottom at the vessel. On taking a drop from the surface, and examining it xinder the microscope, uroglaucin [has the appear- ance of a dark central spot, from which proceed numerous lengthy tentaculte]. To separate the two products of oxidation of urox- anthin, we collect on a filter the sediment thrown down by nitric acid, and agitate it with cold spirit of .830, which takes up the urrhodin, (as also does ether j) the residue is boiled for some time with spirit of the same strength, until the fluid becomes somewhat concentrated; we thus get a bright blue solution of uroglaucin. To exhibit these substances in normal urine, the fluid must be so far evaporated as just to remain liquid. On adding concentrated nitric acid to the cold residue, a' crystalline magmia of nitrate of urea is at once formed; on adding to this a few more drops of niti’ic acid (and sometimes even this is unnecessary) it assumes a violet tint. If the cyrs- talline mass is allowed to stand for some time, and is then dissolved in the smallest possible quantity of distilled water, after being left at rest for some time^ it deposits a sediment in which urrhodin and uroglau-