Complement fixation in tuberculosis / by A.M. Stimson.

  • Stimson, A. M. (Arthur Marston), 1876-
Date:
1915
Catalogue details

Licence: Public Domain Mark

Credit: Complement fixation in tuberculosis / by A.M. Stimson. Source: Wellcome Collection.

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    The low value (25) found above I believe is due to the fact that only 30 minutes elapsed after the giving of the test meal, as Hawk (6) and his collaborators have found that the height of acid and pepsin secretion is not reached in that time. The high value (50) found (see Table I) in a normal individual may be due to a hypersecretion of pepsin, called forth by the high acidity (90). On the following day the same case with a total acidity of 60 showed a peptic value of 41. The limit for normal individuals found so far extends between 25 and 50. The following table gives a comparison of the results obtained on the same contents, by the proposed method and by that of Jacoby: Pepsin number. r | Total Free Case. <a cas ‘ Remarks. acidity. acidity. Proposed Jacoby method. method. 1 51 26 42 100- | Normal 2 55 42 4] 100- (0) 3 58 42 42 100- Do 4 60 45 4] 100- Do oD 69 49 42 100- Do 6 71 49 4] 100- Do 7 71 Do 40 100- Do 8 89 70 40 100- 9 56 31 mk 60-80 | Pellagra 10 57 38 40 100- fo) 11 69 53 33 100- Do By “100—” is meant that the solution is almost clear, only a trace of turbidity being left, the tube contaiming the next bigher concen- tration of gastric content being clear; therefore it is more exact to say ‘100-.”’ From this table it is seen that the values obtained by my method correspond to about four-tenths of those of Jacoby- Solms. BIBLIOGRAPHY. Metts. G, Soums, Eucen. Ztschr. f. klin. Med. 1907, v. 64, p. 159. Rose, Wini1am ©. Arch. Int. Med. 1910, v. 5, p. 459. . GOODMAN, Epwarp H. Am. J. M. Sc. 1908, v. 136, p. 734. . Tichomirow, N. P. Ztschr. f. physiol. Chem. 1908, v. 55, p. 107. . Bercem, Reuruss, and Hawk. J. Biol. Chem. 1914, v.19, p. 345. . NrRENSTEIN and Scuirr. Arch. f. verdauungskrankheiten. 1902. v. 8, p. 559. Berlin klin. Wochenschr. 1903. p. 268. MIO oR WON
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