Volume 1

History and pathology of vaccination / by Edgar M. Crookshank.

  • Crookshank, Edgar M. (Edgar March), 1858-1928.
Date:
1889
Catalogue details

Licence: Public Domain Mark

Credit: History and pathology of vaccination / by Edgar M. Crookshank. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

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    afforded me an opportunity of making further observations upon this curious disease. A mare, the property of a person who keeps a dairy in a neighbouring parish, began to have sore heels the latter end of the month of February 1798, vi^hich were occasionally washed by the servant men of the farm, Thomas Virgoe, William Wherret, and William Haynes, who in con- sequence became affected with sores in their hands, followed by inllamed lymphatic glands in the arms and axiUse, shiverings succeeded by heat, lassitude and general pains in the limbs. A single paroxysm terminated the disease ; for within twenty-four hours they were free from general indisposition, nothing remaining but the sores on their hands. William Summers, a child of five years and a half old, was inoculated the same day with Baker [see description of Plate III., E. M. C], with matter taken from the nipples of one of the infected cows, at the farm alluded to. He became indisposed on the 6th day, vomited once, and felt the usual slight symptoms till the 8th day, when he appeared perfectly well. The progress of the pustule, formed by the infection of the virus, was similar to that noticed in Case XVII. [James Phipps, E. M. C], with this exception, its being free from the livid tint observed in that instance. From William Summers the disease was transferred to WILLIAM PEAD, a boy of eight years old, who was inoculated March 28th. On the 6th day he complained of pain in the axilla, and on the 7th was affected with the common symptoms of a patient sickening with the Small-po.x from inoculation, which did not terminate, till the 3rd day after the seizure. So perfect was the similarity to the variolous fever that I was induced to examine the skin, conceiving there might have been some eruptions, but none appeared. The efflorescent blush around the part punctured in the boy's arm was so truly characteristic of that which appears on variolous inoculation, that I have given a representation of it. The drawing was made when the pustule was beginning to die away, and the areola retiring from the centre.—{Jciinci:) Plate VI. INOCULATED HORSE POX, AFTER TRANSMISSION THROUGH THE COW. Case of Hannah Excell. {JJiNA'£R) following Plate V. April 5th. Several children and adults were inoculated from the arm of William Pead [see description of Plate V.]. HANNAH EXCELL, an healthy girl of seven years old, and one of the patients above mentioned, received the infection from the insertion of the virus under the cuticle of the arm in three distinct points. The pustules which arose in consequence so much resembled, on the 12th day, those appearing from the insertion of variolous matter, that an experienced Inoculator would scarcely have discovered a shade of difference at that period. Experience now tells me that almost the only variation which follows consists in the pustulous fluid remaining limpid nearly to the time of its total disappearance, and not as in the direct Small-pox becoming purulent.—{Jcnner.) Plate VII. INOCULATED COW POX AND INOCULATED SMALL POX. (BALLHOKN AND SIPOMEYER) fachigp. 288 This plate was produced by Ballhorn and .Stromeyer. Traitc de riuoruhfion vaccine, 1801. [It illustrates the results of cultivated vaccine