Text book of comparative general pathology for practitioners and students of veterinary medicine / by Th. Kitt; authorized translation by William W. Cadbury ; edited with notes and additional illustrations by Allen J. Smith.
- Kitt, Th. (Theodor), 1858-1941.
- Date:
- 1906
Licence: In copyright
Credit: Text book of comparative general pathology for practitioners and students of veterinary medicine / by Th. Kitt; authorized translation by William W. Cadbury ; edited with notes and additional illustrations by Allen J. Smith. Source: Wellcome Collection.
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![cause a flocculent precipitate, but which will not (as a rule, and never if certain modes of application are employed) exhibit such precipitating cjualities with any other type of blood. It is inter- . esting in this connection to add that the serum of a rabbit so treated will also precipitate the blood of anthropoid apes, gorillas, orang-outangs and chimpanzees, thus indicating a relationship of these animals to man. Cytolysins and hsemolysins also serve to show the relationships existing between animals in the zoölogical System of Classification. Inasmuch as this reaction is applicable as well with a solution of old and dried blood, the discovery (which as an outcome of research in the field of imrrvunity is due particularly to Bordet, Ehrlich and Morgenroth) has acquired especial importance as a means of information concerning the source of blood stains in forensic medicine. Other albumens may also lead to the formation of specific antibodies in the animal organism, as milk albumen; thus by subcutaneous injection of goat’s milk into rabbits, horses or cows a serum may be obtained which will immediately cause a precipi- tate if it be added to goat’s milk. In the same way, by inocula- tion, coagulins may be obtained for cow’s milk. In the same way, too, in the course of an infectious disease a series of substances are produced in the human or ani- mal organism which render the infectious matter for the time harmless. Should the infectious products develop very rapidly, and by their poisonous properties cause serious protoplasmic changes in the bodv cells, the disturbance is apt not to be limited or checked, and in spite of any reactive-products which may be formed the function of the cells becomes altered and the animal dies. Should the [protoplasmic molecules of these] cells be only partly injured the body prevails over the disease, the molecular defects of the cells becoming regenerated. The surplus of anti- bodies, the result of this regenerative action, are after recovery found circulating in the blood, and in some instances may even pass into the milk. The arnount of protective bodies or anti- bodies in the body-fluids varies according to the intensity of the reaction and the time elapsed after recovery from the infection, the greater part being used up during the course of the disease and the remaining gradually disappearing in metabolism; while with the removal of the Stimulus the supply from the cells tends to cease. If, however, infectious and toxic material be again introduced into the System, stimulating and injuring the cellular](https://iiif.wellcomecollection.org/image/b28130078_0047.jp2/full/800%2C/0/default.jpg)
