Medicines, their uses and mode of administration : including a complete conspectus of the three British pharmacopoeias, an account of all the new remedies, and appendix of formulae / by J. Moore Neligan ; with notes and additions, conforming it to the pharmacopoeia of the United States, and including all that is new or important in recent improvements by David Meredith Reese.
- John Neligan
- Date:
- 1851
Licence: Public Domain Mark
Credit: Medicines, their uses and mode of administration : including a complete conspectus of the three British pharmacopoeias, an account of all the new remedies, and appendix of formulae / by J. Moore Neligan ; with notes and additions, conforming it to the pharmacopoeia of the United States, and including all that is new or important in recent improvements by David Meredith Reese. Source: Wellcome Collection.
Provider: This material has been provided by the National Library of Medicine (U.S.), through the Medical Heritage Library. The original may be consulted at the National Library of Medicine (U.S.)
98/460
![in which colchicum has been employed arc gout and rheumatism, for the former of which it has acquired the character of being a specific. Administered during a paroxysm of gout, it seldom tails to alleviate the pain and cut short the fit; but, so far from prevent- ing a return of the attack, most practitioners agree that the em- ployment of colchicum renders the system more predisposed to the disease, indeed, frequently gives rise to irregular or atonic gout. In acute rheumatism, the employment of colchicum should never be ventured on; but in some of the chronic forms of the disease, especially gouty rheumatism, it is often used in robust constitutions with benefit. Colchicum has also been employed as a cathartic and diuretic in dropsy, and as an antiphlogistic in febrile and in- flammatory diseases; but in the present day its use is almost en- tirely confined to gout and rheumatism. D. & M. of Adm.—In the administration of colchicum or any of its preparations, we should always begin with small doses, and increase them very gradually, as no medicine varies mere in its action on different persons, and, besides, the pharmaceutical prep- arations differ much in activity. It is sold' m us< d in the form of powder: the dose is from gr. ij. to gr. viij.; the powder of the seeds should be preferred to that of the cormus, as being more uni- form.—Acetum Colchici, D. L. E. (Fresh colchicum cormus, sliced, gi.; distilled vinegar, fgxvj.; proof spirit, fiji. ; macerate the col- chicum in the vinegar for three days in a covered glass vessel; press, strain, and set aside, that the dregs may add the spirit to the clear liquor.) [IT. S. P.—Colchicum root, bruised, 2 oz.; distilled vinegar, 2 pints; alcohol, a fluid oz. Macerate the colchicum root with the vinegar in a close glass vessel seven days ; express the liquor and set it aside, that the dregs may subside; lastly, pour off the clear liquor, and add the alcohol. Dilute acetic acid may be substituted for the distilled vinegar.] This preparation is preferred by Scudamore to any other for gout; he recommends it to be combined with magnesia, to sat- urate the acid. It is, however, of very uncertain strength, in con- sequence of being frequently prepared with the dry bulb. Dose, f3ss. to fsij., frequently repeated.— Extract >im Colchici {cormi), L. (Fresh colchicum cormus, ibj.; bruise, with a little water, in a stone mortar; press out the juice and evaporate it, unstrained, to a proper consistence.) Dose, gr. j., every three or four hours; not much used;—Extraction Cokhici {cormi) aceticum, L. E. (Fresh colchicum cormus, Ibj. • acetic (pyroligneous, E.) acid,f|iij.; bruise the cormus* gradually adding the acid; express the juice, and evaporate it in a porcelain vessel not glazed with lead (over the vapour bath, E.) to a due consistence.) Dose, g\\ i. to gr. iij., two or three times a day. Made into pill with an' equal quantity of extract of colchicum, it forms an excellent cathartic in gouty and rheumatic affections.—Oxymel Colchici {cormi), D. (Fresh colchi- cum bulb, cut into thin slices, =i.; d stilled vinegar, f^xvj.; clari- fied honey, by weight, tbij.; macerate the colchicum with the vin-](https://iiif.wellcomecollection.org/image/b21143614_0098.jp2/full/800%2C/0/default.jpg)


