Studies on Rocky Mountain spotted fever / U.S. Treasury Department, Public Health Service.

Date:
[1930]
Catalogue details

Licence: Public Domain Mark

Credit: Studies on Rocky Mountain spotted fever / U.S. Treasury Department, Public Health Service. Source: Wellcome Collection.

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    Figure 1 gives the temperature curves of guinea pigs injected with one infected tick each, taken directly from the ice box. The first four tests were eeacioal out on October 31, 1923, the last three on January 2,1924. In five pigs no fever followed the injection. Two showed an elevation of 39.8° C. and 40° C., respectively, for one day a ee ea 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 26 ; pst bots ashe bod 0 cil gl $8 AS ME AAMNaa eS Zasken se -. (ea ae Pe A a a9 SN LL thledse re iat) a sh nc) A eC ce x Ae Fr ee a re ate ae 47 Ee ee 40° iss ates 3% a pee eat ea wile i ia aw a Fee oe ba See ae oe 39° et is em oo 38° corpealan ead Jon. pallies] + leg exa! el ae a Co Oy 4? Fe eg es ee a lace ak 40° “ SSRe eee 59 ae | IsFltypical_| ES Ee Ge or ool cy ai se | ease ee po hep eve ee Piet eit sepa Pelee date: [3 te th bheald ESSE Sze art tt Pease eee aot | | | | la Ma it ab Pee eee ial ps eh add cL Sh hedheoh ed RAR ee eit 2@2ER R22 Sree e wi ee ee ey Pica eel ee” ee eee so] | Lee ipsa alinels de Vivo ol at ae ee LyDead| |_| pete lc ieee Peer ol cheb eh eT vel le FicgurRE 2.—Lot 2351-B-—(2A). Unfed ticks removed from ice box, incubated 24 hours at 87° C., and injected peritoneally each.? The subsequent injection of blood virus was negative in two pigs, indicating complete immunity. The others developed mild ® We have considered any temperature in guinea pigs above 39.6° C. to be a definite fever, and areas in the chart lying between this line and the temperature curve are shaded in black. While some investigators consider 39.2° C. to be the upper limit of a normal guinea pig’s temperature, it is believed the temperature varies considerably with that of the surrounding air and the age of the animal. Young pigs run a consistently higher temperature than those which have matured
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