The treatment of wound shock / (instructions produced by the Medical Research Council Committees on Traumatic Shock and on Blood Transfusion, in co-operation with the Army Medical Service).

Date:
1944
Catalogue details

Licence: Public Domain Mark

Credit: The treatment of wound shock / (instructions produced by the Medical Research Council Committees on Traumatic Shock and on Blood Transfusion, in co-operation with the Army Medical Service). Source: Wellcome Collection.

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    If an autoclave is not avatlable | Bottles, glass tubing, rubber tubing and rubber bungs can be sterilised by boiling for 20 minutes, preferably in freshly prepared pyrogen-free citrate solution. The needles can be sterilised in liquefied phenol (acidum carbolicum liquefactum) or pure lysol (rinsing in sterile saline before use) or in hot oil. The wire-gauze filter may be boiled in saline or citrate solution. APPENDIX E Concentrated Red Celi Suspension. Although in the initial treatment of wound ‘‘ shock ’”’ the transfusion of whole blood, or serum or plasma in their liquid or reconstituted dried forms, is the best means of restoring blood volume, concentrated red cell suspension may be of value in combating an¥ subsequent anaemia. Such suspension is prepared by taking two Medical Research Council bottles of whole citrated blood of the same group, in which maximum sedimentation of the red cells has occurred (usually 5-6 days after date of collection). The supernatant plasma in each is syphoned off, and the red cell deposit in one bottle added to that in the other, the mixture being topped up to the 540 c.c. mark with a small volume of saline, preferably hypertonic (1-1 per cent.). Sterile precautions are maintained throughout, and it is advisable that the suspension. be used only within a few hours of its preparation. The anticipated rise in haemoglobin resulting from the transfusion of one Medical Research Council bottle of whole blood (with the usual proportion of anticoagulant solution) is approximately 8 per cent. (Haldane scale) in an adult, in the absence of simultaneous blood loss or blood dilution. With concentrated red cell suspension under similar conditions, a rise of about 15 per cent. per bottle may be obtained. The reaction incidence is probably less than with whole blood, serum or plasma. (67627) Wt.2443/930 11/44 Hw. G.344 Pavesi. , Bi i vo ed () ~ ie a | : AY | Ae ah ys