A manual of diseases of the throat and nose : including the pharynx, larynx, trachea, œsophagus, nose and naso-pharynx / by Morell Mackenzie.

  • Mackenzie, Morell, 1837-1892.
Date:
1884
Catalogue details

Licence: Public Domain Mark

Credit: A manual of diseases of the throat and nose : including the pharynx, larynx, trachea, œsophagus, nose and naso-pharynx / by Morell Mackenzie. Source: Wellcome Collection.

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    increased secretion of waterj' fluid containing imijerfectly- developed epithelial cells. The abundant secretion which occurs during life comes not only from the oesopliagus but from the pharynx and the salivarj' glands, which apj>ear to be sympathetically stimulated. Zenker and Ziemssen,* following Klebs, assert that inflammation of the gullet is altogether different from inflammation a.s it aflects other mucous membranes, but this view is not home out by the only case of idiopathic oesophagitis m which the appearances have been recorded. In this instance the follow- ing changes were observed chiefly at the upper and lower ends of the tube “ The mucous membrane was red but not ulcerated, extremely congested and thickened ; the glands were more promment than usual, the mucous membrane was covered in several places with a glutinous grey, or greyish- yellow coating, w'hich could be washed off. On section the submucous tissue appeared to be thickened and infiltrated wdth liquid. Strong pressure between the fingers made it thinner. There was no pus to be seen. ^licroscopically, the viscous coatmg was found to consist of mucus with abundant epithelium cells and pus corpuscles.” - Although as a ride the acute inflammation rapidly sidv sides, yet occasionally it leads to vJceratk/n. This apjiears to have occurred in the case reconled by Paletta,^ in which a young w'oman who died from extensive inflammation of the tlu’oat, involving the pharynx, larjmx, and lesophagus, was found to have a large idcer on the anterior wall of the guUet. Mondiire ^ also mentions the case of a woman who succumhed to an attack of cesojihagitis, terminating after four months’ illness in ulceration of the msophagus, for which there aj)peared to have been no other cjiuse than sini])le inflannnation. It rarely happens that the inflammation leads to the for- mation of a distinct altsa'ss, though this sei|uel is common enough in cases of traumatic origin. Three instances, however, are on record, in which a'sophagitis terminated in ab.scess; in one® of these tlie siic was accidentally opened by the pncssure of a bougie, whilst in tlie others spontaneous rupture occurrt*il, and pus was continuously expectorated, in one case® for three or four days, ami in the other ‘ for a fortnight. > Op. cit vol. viii. n. 13.’). ^ Laboulbeiic: Op. cit. ji. 84. “ Exeri’it. Pathol. ’ 18-20, p. ‘2'28. “Arch. Gihi. de Med.’^ t. xxiv. ® Hourguet; “Gazette de Saute.” 1823, p. 221. « Padova: Loc. cit ■ Harra-s: “Arch Gen. de MW.” 1825.