A report on localised tuberculosis in swine / by A. Eastwood, M.D. and F. Griffith, M.B.

  • Eastwood, A. (Arthur), 1867-1936
Date:
1914
Catalogue details

Licence: Public Domain Mark

Credit: A report on localised tuberculosis in swine / by A. Eastwood, M.D. and F. Griffith, M.B. Source: Wellcome Collection.

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    Liver.—Normal. Spleen.—There were found one hard nodule, about the size of a small pea, composed of caseating tissue, anda minute, grey tubercle with an opaque centre. In smears from these no tubercle bacilli were seen, but from the larger nodule a culture of mammalian tubercle bacilli was obtained, and an emulsion produced general tuberculosis in two guinea-pigs. Summary. Disseminated tuberculosis due to tubercle bacilli of mammalian type, virulent for guinea-pigs and a rabbit. PIG TX VI: Received from Brighton on December 28th, 1911, as a case of slightly disseminated tuberculosis. Submaxillary lymphatic glands.—On one side only there was a single round gland, rather less than 1 cm. in diameter, which con- tained caseous, gritty, miliary nodules. A guinea-pig inoculated developed general tuberculosis, and a culture of mammalian tubercle bacilli was obtained from it, as well as direct from the submaxillary gland. | Mesenteric glands.—Normal. — Lungs.—Beneath the pleura on the left side there was a single small irregular caseous tubercle. On section of the lungs, areas of congestion could be seen, but no tubercles. Bronchial glands.—These were moderately enlarged and were filled with caseous, gritty tubercles aggregated into caseo-calcareous areas. A culture was grown resembling that from the submaxillary gland. Liver.—On section were seen about six caseous, gritty nodules, irregular in outline, and varying from a rape seed to a millet seed in size. Two only were just visible from the surface. There were also some scattered, irregular, necrotic foci on the surface. Portal glands.—Enlarged and extensively caseo-calcareous. A culture of mammalian tubercle bacilli was grown. Spleen.—There were about 20 tubercles, most of them visible beneath the capsule. They were not very evident, being about the size of rape seed, and not easy to distinguish, as they were merely enlarged and congested Malpighian bodies with a slight amount of central caseation. A culture of mammalian tubercle bacilli was grown. Inguinal glands.—Normal. Summary. Disseminated tuberculosis due to tubercle bacilli of mammalian type, virulent for guinea-pigs and a rabbit. ; Pig XXXVII. Received from Birmingham on January 5th, 1912, as a case of apparently localised tuberculosis. Aged 12 or 13 months. Submaxillary lymphatic glands.—On one side were three small glands containing discrete, calcareous granules, easily picked out and situated mainly just beneath the capsule; they also contained small caseo-calcareous nodules, the largest the size of a hemp seed, in
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