Chemo-therapeutic trypanosome studies with special reference to the immunity following cure / by B.T. Terry.

  • Terry, B. T. (Benjamin Taylor), 1876-
Date:
1911
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Licence: In copyright

Credit: Chemo-therapeutic trypanosome studies with special reference to the immunity following cure / by B.T. Terry. Source: Wellcome Collection.

Provider: This material has been provided by London School of Hygiene & Tropical Medicine Library & Archives Service. The original may be consulted at London School of Hygiene & Tropical Medicine Library & Archives Service.

    55/78 (page 51)
    (i) strains that are considered to be specifically distinct, i. e., surra of India and caderas, and (2) those that are regarded as having had a common origin, i. e., surra of India and surra of Mauritius. TRYPANOSOMES SPECIFICALLY DISTINCT. 5/[C], or Surra of India Separated from Caderas.—In order to separate surra of India from caderas, the mixture of parasites was inoculated into mice immunized to caderas. Both animals became infected, presumably with surra of India. In subsequent tests the parasites derived from these animals will be referred to as SI[C]. 1. CDi-f TroI^l 5 SSI+CDi-r '-l. 2. CDi-r ITr^- cAacSl 5 oSI+CDi-? 'o '-^D.' Some Protection Against Surra of India.—In the above experi- ments we apparently have additional evidence that mice cured of caderas acquire a certain resistance to surra of India, for we note that in both tests infection was retarded, and that one of the mice (No. i) recovered completely after being infected as late as the tenth and eleventh days after treatment. The recovery in this in- stance is all the more remarkable because it was in an animal that had received only one injection of trypanred, and in prophylactic experiments, this medicament has failed to protect, even when surra of India was inoculated as early as the third, fourth, and fifth days after treatment. CZ)[/], or Caderas Separated from Surra of India.—In separat- ing caderas from surra of India, the mixture of trypanosomes was inoculated into mice immunized to svtrra of India. 018OL 11 2. Slt^ ^Aa IClI>^^ 5 3. Sli-s +Aa^ ' oCLoWol oSIi-'» 7 4. ^Aa' 'oClI'U 7 All of the inoculations were intraperitoneal and infected within twenty-four hours. The parasites from these mice will be referred toasCD[I]. SSI+CDf-r 1-9 + lop.-. oSI+CDf-s' 8-10 II + 0 oSI+Cd.-^ 13-17 + 18^ i-» ■^SI+CDi^^ 13-17 +