Chemo-therapeutic trypanosome studies with special reference to the immunity following cure / by B.T. Terry.

  • Terry, B. T. (Benjamin Taylor), 1876-
Date:
1911
Catalogue details

Licence: In copyright

Credit: Chemo-therapeutic trypanosome studies with special reference to the immunity following cure / by B.T. Terry. Source: Wellcome Collection.

Provider: This material has been provided by London School of Hygiene & Tropical Medicine Library & Archives Service. The original may be consulted at London School of Hygiene & Tropical Medicine Library & Archives Service.

    56/78 (page 52)
    Purity of SI[C'\.—In the single experiment to test the purity of SI[C], mice were immunized to this virus and then inoculated with surra of India, caderas, and other strains. 1. SlLCr:' 'Mxl ^Mxlcsou *oSl[C]('l 5 cSIf f ' ^ L. 2. SI[C]-'° 'Mxl ^MxlceoL JSI[C]i-.' 5 oSMi-.^ V' ^D. 3. SI[C]-' 'Mxl ^Mxlcso. iSI[C]i-3 5 SCDi-r D.* 4 SI[Cr:'° 'Mxl ^MxlcsoL :si[C].-i 5 oDNi-6 D.'* 5. SI[C]l:' 'Mxl ^Mxlcso. ^SI[C]i-» 5 ING.-S D.'- We note that infection with surra of India was completely pre- vented (mouse I), that it was delayed in the case of surra of Mau- ritius (mouse 2), but that in the tests with caderas, dourine, and nagana it took place at once (mice 3, 4, and 5). From this it would seem that surra of India had been separated in purity from caderas. The resistance manifested in the test with surra of Mauritius is probably to be explained by the close relationship of surra of Mauritius and stirra of India. Purity of CD\^I~\.—In testing the purity of CD [I], only one experiment was carried out. In this the mice were immunized to CD [I] and then inoculated with caderas, surra of India, surra of Mauritius, dourine, and nagana. 10-40 ISO! ° L. 10-41 I80| o l_. 10 11-41 ISOl ♦ o i-. 10-15 HQ 1-J in-IJ 14-18 I9||J vio From the above one might think that the separation of caderas from surra of India had not been effected in purity and that we are here dealing not with caderas,^ ^ but with a mixture of caderas and surra of India, for we note that the tests with surra of India failed as completely as those with caderas. Nevertheless, for the following two reasons it seems quite probable that this view is not correct:-— As in well-staiiTed blood specimens the trypanosomes of caderas are distin- guishable from those of surra of India, it had been planned in this experiment to determine the purity of the separation by means of the microscope. Due to an oversight, however, this test was omitted. 1. CD[I]f4' 'Mxl IMxloisoL iCD[ni^4'° 6 2. Cd[I]i-.' 'Mxl IMxloi8»L ^ 6 oOil-6 3. CT>\ni-t iMxl IMxloisoL 6 4. CDmf-.' ^MXI OMXIOISOL 6 5. CT>mi-i iMxl oMxloISOL 6