Chemo-therapeutic trypanosome studies with special reference to the immunity following cure / by B.T. Terry.

  • Terry, B. T. (Benjamin Taylor), 1876-
Date:
1911
Catalogue details

Licence: In copyright

Credit: Chemo-therapeutic trypanosome studies with special reference to the immunity following cure / by B.T. Terry. Source: Wellcome Collection.

Provider: This material has been provided by London School of Hygiene & Tropical Medicine Library & Archives Service. The original may be consulted at London School of Hygiene & Tropical Medicine Library & Archives Service.

    59/78 (page 55)
    An inoculation on the eleventh day (mouse i) failed, and an- other on the sixteenth (mouse 2) infected only after an incuba- tion period of eight days (control positive on the first day). As the starred^'' virus differs in no important respect from SI[M], the results of tests with these two strains are at times given together, nevertheless these strains are always distinguished. (2) Mice cured of surra of Mauritius possessed little or no im- munity to 1. SMiNu JAa' cClo.»ol 4 SM: +MA oOLoiso 4 5. SM ': 18OL 6 12 12 oSiiM-]i-r cSI[M]i^3^ oSI[M-].^r 'cSI[M]3'-^ '^irMit-,' u-16 + 14-82 ^si[M]f-'r 23Q I-10 S0Q1-S All of the tests infected, and in four of the five animals, para- sites appeared within twenty-four hours. In the mouse in which infection was delayed, the trypanosomes were found on the day after they were seen in its control. (3) Mice immunized to SI\_M^ acquired a perfect immunity to surra of India (Nos. i and 5), reacted in a variable zvay tozvard surra of Mauritius {Nos. 5 and 6), and became infected zvithin ttventy-four hours zvhen tested zvith , caderas, doctrine, and D. nagana. 1. SlMf-.' iAA^- ^Cl'!- 5 oOll-J oOll-J 2. SI[M]i-^ ^Aa'- SCl'!- 5 oSI[M]^ 3. SI[M]^^: ^Aa ICl'!' 5 SSM' '^SM.-i' 4. SI[M]f-^ ^Aa'' lOC^ 5 'o*SM[I]f- SM[l].--a 5. SM-'-' 'MXI ^XlolSOL ^siDycf'i 5 iSIi-f 6. SICM]'' 'MXI OMX10180L oSI[M]f'l 5 ISMi-l 7. SIM' 'Mxl oMxloiwL ^SI[M]fA^ 5 ICDi-f 8. SICM] -' 'Mxl oMxloisoL JSI[M]i'-l 5 tDTsn y. SICM]!' iMxl oMxlo.80L oSiaof-? 5 lNoi-4' 13 U-97 + O H-J8 SJ-S7 »-ti + D. * .5Q I 7 This virus resembles SI[M] in that it was obtained by infecting with surra of India a mouse immunized to surra of Mauritius. It differs from SI[M] in that the immune mouse was inoculated, not with a mixture of surra of India and surra of Mauritius, but with surra of India alone.