Chemo-therapeutic trypanosome studies with special reference to the immunity following cure / by B.T. Terry.

  • Terry, B. T. (Benjamin Taylor), 1876-
Date:
1911
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Licence: In copyright

Credit: Chemo-therapeutic trypanosome studies with special reference to the immunity following cure / by B.T. Terry. Source: Wellcome Collection.

Provider: This material has been provided by London School of Hygiene & Tropical Medicine Library & Archives Service. The original may be consulted at London School of Hygiene & Tropical Medicine Library & Archives Service.

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    one being seen in one hundred fields of the injected suspension (controls positive on the second day). (3) In the prophylactic experiment with this virus be- haved more like surra of Mauritius than surra of India. 2. Cl'° 0 *SM[nt-,\ '*D/- One mouse (the first ) resisted infection and the other had a re- lapse on the twentieth day. In similar tests with surra of India both animals remained negative; and in those with surra of Mauri- tius one remained negative, the other relapsed, just as in the experi- ment above. In the other tests, SM[I'\ acted anomalously, but scarcely more so than pure surra of Mauritius had done. In some, it behaved like surra of India (see first and second experiments below), in others like neither surra of India nor surra of Mauritius. The experiments which resulted anomalously follow. 1. Mice immunized to surra of India were immune to 1. SI':* ^Aa^ ^CLi*i«.L 9 '^SMffl^'-ro -o' L. ,2. ST- iAA'° oCLoi-80L 11 '^SM[I].'-o' z'' 'V In the first mouse, infection was completely prevented. In the second, it was delayed and was followed by an irregular and pro- longed course (death on fifteenth day after inoculation). 2. Mice immunized to acquired an immunity to surra of India (No. 4) but none to surra of Mauritius (No. i) or to caderas (Nos. 2 and 5). 2. SM[I]i-f ^ClS^o 7 ^Cd>-.' D.'-' 3. SMIHi-f JClSjo 8 lOsl-r 'V- D.* 4. SMmi-f ^ClI>^:o 8 iSllt 'SSL-s' o' D. 3. A mouse immunized to both surra of India and ^urra of Mauritius offered little or no resistance to infection zvith SM[I]. 1. si+SMi'-'r ^Aa° ^CLi'i-«,L 5 '2SM[i]i=^'r 12-lS 14 16-18 19- 25 27-29 Mr In this test infection was manifest on the day after the parasites were found in the control. We note, however, that the mouse sub-