Research into the chemical processes in the small intestine of man / by Allan MacFadyen, M. Nencki and N. Sieber.

  • Macfayden, Allan, 1860-1907.
Date:
[1891]
Catalogue details

Licence: Public Domain Mark

Credit: Research into the chemical processes in the small intestine of man / by Allan MacFadyen, M. Nencki and N. Sieber. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

    10/46 (page 396)
    July 7.—Discharge semifluid; faintly acid and almost odourless; a marked peptone reaction ; sugar = D58 per cent. 2’9276 grms. dried at 110° C. yielded 0’1937 grm. = 6‘52 percent, dry substance. After combustion the amount of nitrogen gas was 12‘4 c.c. at 21° C. and 707 mm. bai-ometric pressure. The percentage amount of nitrogen in the dry remainder was therefore 6'78 per cent.; in the fresh intestinal contents 0‘44 per cent. From the 10th to the 18th July the patient was given at noon boiled peas instead of barley gruel. On the first day she complained of loss of appetite, so the peas were given to her mashed—140 grammes daily. Discharge on July 10.—Two portions were received from the hospital: (1) 120 grammes semifluid discharge, which was passed after the usual diet of meat and barley gruel. The reaction was acid. Sugar =1*8 per cent. (2) 83 grammes thick consistent discharge, passed at 5.30 p.m., after the patient partook of boiled green peas at 12 o’clock noon. It was filled with swollen undigested peas. The reaction was acid. July 11.—Discharge porridge-like. Acid reaction. Microscopically were seen numerous cells filled with starch granules, more rai*ely muscular fibres. A portion of the discharge was semifluid. The whole was mixed with water and filtered. In the filtrate were sugar and albumen. On adding acetic acid, no cloudy precipitate. July 12.—The discharge was thinner and more fluid. Numerous cells containing starch were present. Acidity = 0*163 per cent. July 13.—Reaction acid; odour, faintly putrefactive. In the filtrate was 0*95 per cent, sugar. July 14.—Discharge thickish; acid, with a faint putrefactive odour. A portion was dried for an elementary analysis. 3*3624 grammes dried in a platinum vessel gave 0*2982 grm. remain- der. Dry remainder therefore = 8*87 per cent. The nitrogen estima- tion gave 12*6 c.c. N gas at 22° C., and 713 mm. bar. pressure, i.e., 4*49 per cent. N in the dry remainder, or 0*398 per cent. N in the fi*esh moist substance. Further, 3*4518 grms. moist substance gave 0*3062 grm. dry re- mainder. The combustion in an oxygen current with CuO, gave 0*4987 grammes COg, and 0*167 grm. HgO = 44*41 per cent. C. and 6*05 per cent. H. The remainder of the discharge, as well as that of the 14th, 15th, and 16th July, was dried and utilised for an ash estimation. July 18.—Discharge thickish, reaction acid. It contained numer- ous muscular fibres, and was the first passed after stopping the pea diet. July 19.—Discharge thickish and consistent, and contained many muscular fibres. The filtrate was acid, and contained only traces of sugar and albumen. The albumen was first precipitated after adding ammonia. Acetic acid gave no cloudy precipitate. July 23.—Discharge consistent and acid—sugar =0*47 per cent. The solid remainder was estimated, as well as the substances soluble in ether. 2*453 grammes gave 0*2754 grm. dry remainder = 11*23 per