The constituents of bryony root / by Frederick B. Power and Charles W. Moore.
- Frederick Belding Power
- Date:
- [1911?]
Licence: In copyright
Credit: The constituents of bryony root / by Frederick B. Power and Charles W. Moore. Source: Wellcome Collection.
9/14 page 943
![The substance thus agrees in composition with a phytosterol, and it yielded the colour reactions of that class of compounds. It was found fo be optically inactive, as was also the case with the phyto sterol obtained by the present authors from colocynth, although the two compounds are not identical (compare Trans., 1910, 98, 105). The acetyl derivative, when crystallised from acetic anhydride, separated in glistening plates, melting at 155—157°. Isolation of a New Dihydric Alcohol, Bryonol, C22H3402(0H)2. The alkaline liquid, which had been extracted with ether as above described, was acidified, and again extracted with ether. The ethereal extracts were united, after which a quantity of an almost colourless, sparingly soluble substance which accompanied them was separated by filtration. This substance was crystallised, first from a mixture of pyridine and ethyl acetate, and then from glacial acetic acid, when it was obtained in small, colourless plates, melting and decomposing at 210—212°. The quantity so obtained was about 0'8 gram: 0T324 gave 0-3508 C02 and 0T210 H20. C = 723; H = 10T. C22H3604 requires C = 72‘4; H = 99 per cent. This substance, when dissolved in chloroform with a little acetic anhydride, gave, on the addition of a few drops of concentrated sulphuric acid, a series of colour reactions similar to those produced by the dihydric alcohol ipurganol, C21H3202(0H)2 (Tower and Rogerson, J. Amer. Chem. Soc., 1910, 32, 89), and it appears, in fact, to be the next higher homologue of the latter. Like ipurganol, it dissolves in concentrated sulphuric acid with a yellow colour, the solution showing a green fluorescence. No substance possessing the formula of that above described appears to have hitherto been recorded. Being, therefore, a new compound, it is proposed to designate it bi'yonol, with reference to the generic name of the plant from which it has been isolated. Diacetylbiyonol, CgoII^O^CCbCHg);,.—This was obtained by heating bryonol with acetic anhydride. It crystallises from alcohol in long needles, melting at 152°: 01184 gave 0'3000 C02 and 0'0960 H20. C = 69‘l; H = 9 0. C26II40O6 requires C — 69'6; H = 8’9 per cent. From the above results it is evident that bryonol belongs to a group of dihydric alcohols which are represented by the general formula CnII2n_s04. The knowm members of this group, all of which have been isolated in these laboratories, now comprise the following compounds: ipurganol, C2]H3202(0H)2 (loc. cit.); bryonol,](https://iiif.wellcomecollection.org/image/b30618186_0009.jp2/full/800%2C/0/default.jpg)
