The localisation of cerebral disease : being the Gulstonian lectures of the Royal College of Physicians for 1878 / by David Ferrier.
- Date:
- 1878
Licence: Public Domain Mark
Credit: The localisation of cerebral disease : being the Gulstonian lectures of the Royal College of Physicians for 1878 / by David Ferrier. Source: Wellcome Collection.
Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.
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![and limits of these centres. With these facts, however, the case IS altogether altered. Unilateral Oculo-motor Monoplegia.—At the base of the first frontal, and extending partly into the second frontal convo- lution m the brain of the monkey, there is an area ([12] figs. 26 and 27) irritation of -which causes elevation of the eyelids, dilatation of the pupils, conjugate deviation of the eyes and turning of the head to the opposite side. I have placed these various reactions in the order in which they occur with slight and longer continued stimulation respectively. In the faintest form of stimulation, elevation of the eyelids is the only effect observable. Whether individual centres, incapable of sharp demarcation from each other for each of the movements indi- cated, exist here, has not been determined experimentally. There are, however, clinical facts which seem to require the existence of a distinct centre for the levator palpebrse superioris, inasmuch as paralysis may occur, limited to this muscle without affecting the other muscles supplied by the third nerve; an occurrence difficult to explain by peripheral affection of this nerve. Some such cases have been observed in connection with disease of the cortex, and attempts have been made, but not, I think, successful or in accordance with experimental lesions, to localise this centre in the angular gyrus.' If a distinct voli- ' Landouzy, ' Blepliaroptoso C^rebrale.' Archiv. Gin. de Mid., August 1877- Landouzy has brought together the cases which have been reported (by](https://iiif.wellcomecollection.org/image/b21930582_0074.jp2/full/800%2C/0/default.jpg)