Volume 1
Lectures on surgical pathology : delivered at the Royal College of Surgeons of England / by James Paget.
- James Paget
- Date:
- 1853
Licence: Public Domain Mark
Credit: Lectures on surgical pathology : delivered at the Royal College of Surgeons of England / by James Paget. Source: Wellcome Collection.
Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)
458/524 page 440
![normal movements of the blood are adequate to the expla- nation of the ordinary process of nutrition. II. We may speak much less equivocally of the influence of the state of the blood itself in causing inflammations; for there can be little doubt that a very great majority of the so-called spontaneous or constitutional, as distinguished from traumatic, inflammations, have herein their origin. We might anticipate this from the consideration that, in normal nutrition, the principal factors are the tissues and the blood in their mutual relations : but we have better evidence than this, in cases of local inflammations occurring in consequence of general diseases of the blood. Some instances of this are clearly proved, as, e. g. in the cases of eruptive fevers, when the presence of morbid materials in the blood is proved by the efi'ects of their transference in inoculation. Scarcely less thoroughly demonstrated are the cases of rheumatism and gout, of lepra, psoriasis, herpes, eczema, erysipelas, and other such affections, whose consti- tutional nature—in other words, whose primary seat in the blood—a,ll readily acknowledge in practice, if not in theory. Now, in all these cases, local inflammations are the ex- ternal signs of the general affection of the blood : and I apprehend, that if any difficulty be felt in receiving these as evidences, that the morbid condition of the blood is the cause of the local inflammation, it will be through doubt whether a general disease of the blood—a disease afiecting the blood sent to every part—can produce peculiar pheno- mena of disease in only certain small parts or organs. But this local effect of a general disease of blood has its illus- tration in some of the sure principles of physiology; espe- cially in one which I have fully illustrated in a former lecture (p. 27 et seq. and ]). 63); namely, that the presence](https://iiif.wellcomecollection.org/image/b2128913x_0458.jp2/full/800%2C/0/default.jpg)


