New medications / By Professor Dujardin-Beaumetz ... Tr. by E. P. Hurd.

Date:
1890
Catalogue details

Licence: Public Domain Mark

Credit: New medications / By Professor Dujardin-Beaumetz ... Tr. by E. P. Hurd. Source: Wellcome Collection.

Provider: This material has been provided by the Harvey Cushing/John Hay Whitney Medical Library at Yale University, through the Medical Heritage Library. The original may be consulted at the Harvey Cushing/John Hay Whitney Medical Library at Yale University.

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    mixture a tablespoonful may be given, morning, noon, and night. The prescription may be written as follows: ^ Alcoholic sol. trinitrin (i per cent.) gtt. xxx. Water, grammes ioo (J x). M. Sig.: A tablespoonful three times a day. You can also employ the hypodermic method, using the following solution: 5 Sol. trinitrin (i per cent.) gtt. xxx. Cherry laurel water, grammes x. M. Sig.: For subcutaneous use. Every fifteen minims contains three drops of the solution of trinitrin.* When you study the physiological action of this medicine, you observe that as far as the toxic proper- ties are concerned, experimentors have advanced opinions the most opposite, and while Bruel regards it as one of the most energetic poisons, we see Vul- pian, on the contrary, maintain that its action is al- most nil in animals; and in the experiments which I undertook anew with De Marieux, who has written an admirable thesis on the subject, we discovered why the objection exists. It is, in fact, because, while trinitrin seems to have a very energetic action on man, its physiological effects are scarcely appre- * In American practice the tablet triturates, each contain- ing one minim of the centestimal solution of nitro-glycerin, are chiefly employed.—Ed.]