Researches on phthisis: anatomical, pathological and therapeutical / by P. C. A. Louis.

  • Pierre Charles Alexandre Louis
Date:
1844
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Licence: Public Domain Mark

Credit: Researches on phthisis: anatomical, pathological and therapeutical / by P. C. A. Louis. Source: Wellcome Collection.

Provider: This material has been provided by The University of Leeds Library. The original may be consulted at The University of Leeds Library.

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    The submucous tissue forming the fundus of the ulcerations was sometimes thickened; and in one case, that of the single large ulceration, destroyed in some points. When the ulcerations were unaccompanied with any other alteration of the mucous membrane, the history of the symptoms led to the inference that their formation had occurred some length of time before death. § 7. Other morbid changes of the Mucous Membrane of the Stomach. In six subjects in whom no alteration in respect of consis- tence or thickness of the membrane existed, I found it of a more or less bright red colour throughout its entire extent; the red- ness disappeared after two or three hours' maceration. Gastric symptoms had exhibited themselves in several cases two or three days before death, (Case ii;) so that the change in question may, on anatomical and symptomatical grounds, be regarded as the produce of recent and slight inflammation. I have four times seen the mucous membrane of the stomach excessively softened in the greater part of its upper extremity, without coexisting change of colour or thickness; in these cases I did not observe any notable gastric symptoms. In a subject who died the day of his admission into hospital, the mucous membrane of the stomach exhibited seven large mammillse, nearly uniformly disseminated over its sui'face, and measuring from about two to three lines [4 to 6 millimeters] in diameter, and two lines [4 millimeters] in height. The mu- cous tunic was itself slightly red, of good consistence, and about one line [2 millimeters] thick in these places. About an inch and two lines [3 centimeters] below the cardiac orifice the membrane was slightly prominent, and raised up here by a blueish-white liquid, rather viscid, very imperfectly soluble in water, and contained in a certain number of small cells deve- loped in the submucous tissue. Lastly, one phthisical subject exhibited an example of a sort of cicatrization of the mucous membrane of the stomach ; and another, of the transformation of a limited extent of the mus- cular coat into cartilaginous tissue,—rare species of change, which I shall describe with care further on. (Cases xiv, xv.)