Researches on phthisis: anatomical, pathological and therapeutical / by P. C. A. Louis.

  • Pierre Charles Alexandre Louis
Date:
1844
Catalogue details

Licence: Public Domain Mark

Credit: Researches on phthisis: anatomical, pathological and therapeutical / by P. C. A. Louis. Source: Wellcome Collection.

Provider: This material has been provided by The University of Leeds Library. The original may be consulted at The University of Leeds Library.

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    extent of about one inch and two lines [3 centimeters]. Near tlie neck destruction, similar in kind but less in amount, was visible, where the membrane was a quarter of a line [half a millimeter] thick, and exhibited on a small scale the aspect of a columnar bladder. The submucous cellular membrane had undergone similar thickening; in the situation of the ulcera- tions it was brittle; the gall-bladder contained about two hundi'ed calculi, the largest of which equalled a pea in size, the smallest a millet-seed. Two years before death, the patient had had severe pain in the region of the gall-bladder, and attacks of jaundice frequently recurring during a period of eleven months. In three females, aged thirty, thirty-four, and sixty years, the gall-bladder, exhibiting no diseased change in its coats, contained a considerable number of calculi, in the midst of a great quantity of bile: there had been no symptoms indicative of their existence, and the patients had died at different periods of the year, in spring, summer, and autumn. I have also, in subjects cut off by various chronic affections, and more especially in those affected with disease of the liver (perhaps chronic hepatitis), met with biliary calculi, and thick- ening and ulceration of the walls of the gall-bladder. These morbid states were even of somewhat more frequent occurrence in this category of cases than in those of phthisis. Ulcerations did not always coexist with biliary calculi; but I have never observed the former, unless where a greater or less number of the latter were contained in the gall-bladder. Some of these formations, also, presented themselves in the majority of cases of simple thickening of the mucous tunic.