Chemical examination of the root and leaves of Morinda longiflora / by Marmaduke Barrowcliff and Frank Tutin.

  • Barrowcliff, Marmaduke.
Date:
[1907?]
Catalogue details

Licence: In copyright

Credit: Chemical examination of the root and leaves of Morinda longiflora / by Marmaduke Barrowcliff and Frank Tutin. Source: Wellcome Collection.

    12/16 page 1916
    after crystallisation from ethyl acetate, melted at 151—152° and gave the reactions of anhydrous citric acid. The filtrate from the lead acetate precipitate was freed from lead, and concentrated. It was found to contain a large amount of a hexose, as it readily yielded d-phenylglucosazone melting at 216°. II. Examination of the Leaves. The ground leaves (5*8 kilograms) were completely extracted by continuous percolation with hot alcohol, the liquid concentrated, and the residual dark green extract mixed with water and distilled with steam. The distillate, on extraction with ether, gave a small amount of an essential oil possessing an unpleasant odour, and the aqueous liquid from which this had been removed was found to contain formic,, acetic, and butyric acids. The distillation flask then contained a quantity (135 grams) of dark green resin, which was separated from the aqueous liquid and well washed with hot water. Examination of the Resins. The resinous mass was dissolved in alcohol, the solution mixed with purified sawdust, and the mixture dried, after which it was extracted successively in a Soxhlet apparatus with light petroleum (b. p. 33—50°), ether, chloroform, ethyl acetate, and alcohol. Petroleum Extract of the Resins. The petroleum extract amounted to 59 grams. It was dissolved in ether and the resulting liquid extracted successively with solutions of sodium carbonate and potassium hydroxide. The products obtained by this treatment were small, and yielded nothing definite, although the liquid obtained on shaking with the latter alkali had a violet colour. The ethereal solution was then evaporated, the residue dissolved in an alcoholic solution of potassium hydroxide, and the mixture heated for two hours. The greater part of the alcohol was then removed, water added, and the alkaline liquid extracted with ether. The ethereal liquid thus obtained yielded, on evaporation, an oily product, which was distilled under diminished pressure. The dis¬ tillate deposited a solid on standing which, when crystallised from ethyl acetate, formed leaflets melting at 68° : 0-0816 gave 0-2551 C02 and 0-1085 H20. C = 85-3 ; H = 14 8 C31H64 requires C = 85'3 ; H=14-7 per cent. This substance was therefore the hydrocarbon hentriacontane.
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