Thoughts, observations and experiments on the action of snake venom on the blood : with an appendix / by George Britton Halford.
- Halford, George Britton
- Date:
- 1894
Licence: Public Domain Mark
Credit: Thoughts, observations and experiments on the action of snake venom on the blood : with an appendix / by George Britton Halford. Source: Wellcome Collection.
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![germinal matter, although they were most carefully sought for. The only cells which we could find were the hen 1 thy red and white corpuscles. In this case, where death occurred in six hours, and where sufficient time had been given for blood changes, I think that if the changes described by Professor Halford always take place, they ought to have been detected. [The large cells, to the best of ray belief, were seen by Dr. Fayrer and Dr. Macnaraara in the blood of a fowl, but not recognised by them as those so frequently described by me.] A full-grown clog was bitten by a large cobra, died in twenty-six minutes. Blood examined just after death coagulated firmly. A half-grown domestic fowl was inoculated on the inner side of the right thigh with the poison taken from a cobra on the spot. Died in three hours. ''Necroscopy.—In the dog's blood, nothing remarkable was observed. The red corpuscles seemed unaltered, and the white corpuscles were present in the usual proportion. But in the fowl's blood, the appearances were remarkable. In this case, death occurred slowly —in three hours ; whereas in the dog, it took place in twenty-six minutes. On carefully examining the fowl's blood with the fa object glass, and an A eye- piece, the following appearances were observed:— The oval red corpuscles were unaltered; but in the field of the microscope, in addition to the blood corpuscles, a number of large granular bodies were to be seen, which, after careful examination, were discovered to be contained within a distinct cell- wall. The granular bodies were coloured by an ammoniacal solution of carmine, but neither the cell- wall enclosing them nor the red corpuscles were](https://iiif.wellcomecollection.org/image/b20395565_0023.jp2/full/800%2C/0/default.jpg)
