Lectures on auto-intoxication in disease, or, Self-poisoning of the individual / by Ch. Bouchard ; tr., with a preface and new chapters added, by Thomas Oliver.
- Charles-Joseph Bouchard
- Date:
- 1906
Licence: Public Domain Mark
Credit: Lectures on auto-intoxication in disease, or, Self-poisoning of the individual / by Ch. Bouchard ; tr., with a preface and new chapters added, by Thomas Oliver. Source: Wellcome Collection.
Provider: This material has been provided by the Francis A. Countway Library of Medicine, through the Medical Heritage Library. The original may be consulted at the Francis A. Countway Library of Medicine, Harvard Medical School.
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![feeble toxicity. It required, on an average, 110 to 140 cubic centimeters for every 55 to 75 kilograms of living tissue. Death was never immediate; it never occurred until from twelve to thirty hours after the injection. The principal effects observed were a fall of temperature and hemoglobinuria. Cabitto in- jected the perspiration of epileptics after convulsive attacks and found that it killed animals in doses of from 15 to 20 cubic centimeters. During the course of certain infectious diseases, notably small-pox, Quierolo noticed that the toxicity of sweat increased. This, too, occurred in malaria. As regards perspira- tion, there is always the probability that the discharge contains numerous microbes the influence of which must not be under- rated when this liquid is injected into animals. Perspiration contains from 990 to 995 parts of water per 1000 and urine from 956 to 9G0. Charrin (Les Defenses Naturelles de l'Or- ganisms) remarks that, while fatal accidents are induced after injecting from 40 to 50 cubic centimeters of urine per kilogram of animal, it requires 70 of sweat, and even with this quantity death does not occur until several hours afterward. A liter of liquid leaving the human body by the kidneys carries an amount of poison capable of killing 20,000 grams of living matter, while the same quantity of liquid escaping by the skin only destroys, and that slowly, 14,000 grams.]](https://iiif.wellcomecollection.org/image/b21176188_0043.jp2/full/800%2C/0/default.jpg)
