A practical treatise on variola ovina, or small-pox in sheep, containing the history of its recent introduction into England; with the progress, symptoms, and treatment of the disease ... / [James Beart Simonds].

  • Simonds, James Beart.
Date:
1848
Catalogue details

Licence: Public Domain Mark

Credit: A practical treatise on variola ovina, or small-pox in sheep, containing the history of its recent introduction into England; with the progress, symptoms, and treatment of the disease ... / [James Beart Simonds]. Source: Wellcome Collection.

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    Twelfth day.—The cuticle covering the inoculated places has a yellow hue, and looks as if it would des- quamate without vesication. All symptoms of the eruption have passed off. Fourteenth day.—It is evident that sloughing will take place around the incisions. Sixteenth day.—The vitality of large portions of the dermis has been destroyed, and their separation has commenced. Twentieth day. — Extensive sloughs have been thrown off; the ulcers however look healthy. The great liability of the inflammation of the inocu- lated places to produce ulceration is undoubtedly dis- advantageous, and must prove an obstacle to the extension of the ovation. Whether sloughing would follow the use of lymph which had been passed through the systems of a number of healthy sheep in succession, can only be ascertained by diversified and well-arranged experiments. Primary lymph is evidently too virulent ; and some plan to mitigate its local effects must be devised before inoculation can become general. The statements of the continental writers are contradictory with reference to the change which takes place in the lymph by transmission from sheep to sheep. Some maintain that it destroys its specific properties, so that it no longer induces a disease which will secure the animal against the small-pox; while others contend that, after several transits, a lymph equally as protective, but far less virulent, is produced. Mr. Mayer, in an article chiefly translated from Hurtrel D’Arboval, and to which we have before referred, states, that “ after the same matter [lymph] has passed through twelve or fifteen lots of sheep, it loses its efficacy, and requires to be