The differential blood count in dengue / by W.L. Harnett.

  • Harnett, W. L.
Date:
1913
Catalogue details

Licence: Public Domain Mark

Credit: The differential blood count in dengue / by W.L. Harnett. Source: Wellcome Collection.

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    1911) saw no instance in 109 cases in the 27th Punjabis at Alipore, nor do McCarrison or Wall describe it as characteristic of the Chitral fever. My experience is the same, but that the pain does occasionally assume this form I can vouch for, as I saw two cares in Europeans in which this very term was used by the patients themeelves, who, when questioned, assured me that they had not only never read any medical book but had never before heard of dengue. One of these patients in the letter asking me to come and see him wrote —“It began yesterday with a slight pain in my left foot.........to-day the whole of my body feels as if there isn’t a single whole bong in it.” Does not this read like a plagiarism from Manson ? The rash is generally agreed to be a variable feature, it is in my experience much more difficult to detect in Indian patients than in Europeans and Eurasians, the few cases which I saw of the latter races all had well marked rashes appearing about the 5th or 6th day, whereas in Indian cases it was either never detected at all, or was very slight and evanescent. The appearance of the rash was always immediately followed by the disappearance of the pains. . Tur BLoop CHANGES. The recorded blood changes in dengue are (1) a marked leucopenia setting in after the 2nd or 3rd day of the fever ; (2) a diminution of the polymorphonuclears ; (3) a marked relative and some actual increase of the large and small mononuclears. (1) Leucopenia I find to be invariable during the febrile stage and is ueuvally well marked after the second day. Lack of time prevented me from counting the total number of leucocytes except in a few cases, but in those which were counted [ found the number of leucocytes to he 3000-4000 per emm. From the appear- ance of the films I judged in the other cases that the numbers present did not ditfer widely from the above. (2) The reduction in the polymorphonuclears becomes manifest at the same time as the leucopenia and continues to progress as other varieties of leucocytes increase during the next few days, (3) The large mononuclears (large hyalines) rarely show any wide departure from the normal in most cases they are slightly diminished in numbers. The lymphocytes, both large and small, at first relatively
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