Preservatives and other chemicals in foods: their use and abuse / by Otto Folin.
- Otto Folin
- Date:
- 1914
Licence: Public Domain Mark
Credit: Preservatives and other chemicals in foods: their use and abuse / by Otto Folin. Source: Wellcome Collection.
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![effects and the effects resulting from repeated administrations of the drug [rabbits cannot vomit]. A definite mini¬ mum toxic dose for rabbits could not be found. The effective dose varied consid¬ erably and lay between seven-tenths gram and one and one-tenth gram ben¬ zoic acid per pound of animal.” According to this report four-tenths of one gram of benzoic acid per pound of dog, or seven-tenths of one gram per pound of rabbit, is necessary to produce the characteristic symptoms of benzoic acid poisoning, and smaller amounts pro¬ duce no demonstrable effects of any kind. The smaller figure (obtained in the case of dogs) would correspond to sixty grams of benzoic acid in the case of a man weighing one hundred and fifty pounds. The Referee Board concluded that four grams per day is harmless. It will be observed that the German report does not deal with the effects of](https://iiif.wellcomecollection.org/image/b31345670_0036.jp2/full/800%2C/0/default.jpg)
