On diseases of the veins, hæmorrhoidal tumours : and other affections of the rectum / by Henry Lee.

  • Lee, Henry, 1817-11 June 1898
Date:
1866
Catalogue details

Licence: Public Domain Mark

Credit: On diseases of the veins, hæmorrhoidal tumours : and other affections of the rectum / by Henry Lee. Source: Wellcome Collection.

Provider: This material has been provided by The University of Leeds Library. The original may be consulted at The University of Leeds Library.

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    If covered with fibrin, this may remain firm, or it may itBol become softened down and find its way into the circulation In old aneurismal sacs such portions of fibrin may be founc softened and containing globules of various sizes, some nol unhke pus, but not acted upon in the same way by acetic acid. Concretions of the above land are usually fomid in cases where the product of fatty degeneration has become mixed with blood, or where portions ol liquefied fibrin have been poured into the circulation. If 'then we find fatty degeneration in diseased arteries mixed, it may be, with Hquified fibrin, and find, moreover, these very same conditions of the fibrinous concretions in the arteries themselves, or their branches, it is impossible to avoid the conclusion, that the diseased condition of the artery is, in many cases at least, the real cause of these fibrinous coagula. When found within the arteries these deposits undergo most important changes. They are at first Httle on not at all adherent to the healthy parts of the vessels. The^ may be carried, in larger or smaller portions, along the com-se of the circulation till arrested either in the smaller tubes ( ir in the actual substance of organs. Wheresoever they st^ ]i. other changes occur. In some cases the fibrin, adhering in its new bed to surrounding parts and becoming absorbed, may cause a puckering and contraction of sm-rounding parts. Nearly all arteries that have been thus obstructed, have been foimd contracted after a certain time. This is so generally the case, that Professor Tiedemann, in describing this disease, has assumed for his title Arctaiion and closure of the arteries. In general, however, post-mortem ■ examinations reveal that softening, accompanied by fatty degeneration, has taken! place in portions of fibrin that have been stopj)ed in their course. When this occurs, the arrested fibrin first becon - attached to adjacent parts. If this arises in one of the larger arteries of a limb, it may so impede the cnculation as to induce gangrene ; if in the structm'e of organs, it is more frequently accompanied by softening of the part. Tliis softening is a molecular necrosis. If we find then, as the result of disease of