Ferment actions of the pancreas in different animals / by Vincent D. Harris and William J. Gow.

  • Vincent Dormer Harris
Date:
1892
Catalogue details

Licence: Public Domain Mark

Credit: Ferment actions of the pancreas in different animals / by Vincent D. Harris and William J. Gow. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    have been after all more with regard to details. Of these it is un- necessary to do more than mention the most important, viz. those of Heidenhain*, Kiihne®, Langley®, Lea^ Bernstein® and Eoberts®, as they have been for the most part introduced into the ordinary text-hooks of physiology. From these observations, however, it has been clearly established firstly, that very definite ferments exist in pancreatic juice, and may be extracted from the gland by means of glycerin and other vehicles; secondly, that these ferments have special relations to the different classes of food stuffs; and thirdly, that during secretion the ferments which had been previously deposited within the pancreatic cells in granular and undeveloped form are discharged into the lumen of the tubes. Although many different animals appear from incidental mention to have been used for the purposes of experiment by different workers, yet we are unaware of any systematic endeavour to investigate the question whether the ferments, four in number, which the pancreas is said to possess, appear in the gland in all animals, and it was with the idea of testing this question in a number of different kinds that this research was done. Section I. The experiments under the first head, viz.: to ascertain whether the usual ferments are present in the pancreases of such mammals as Ave were able to obtain, may be treated of in two divisions, (a) qualitative experiments and {h) quantitative experiments, the former having to do with four different ferment actions and the second with two only. (a) Qualitative Expenments. Experiments more or less complete have been made with the pancreases of the following animals to discover whether they contain ferments, (i) converting starch into sugar, i.e. diastasic or amylolytic; (ii) converting proteids into peptones, i.e. proteolytic; (iii) splitting fats into their fatty acids and glycerin, i.e. lipolytic, and (iv) curdling milk, i.e. rennettic. > PJliiger’s Archiv, x. 567, and xrv. 437 et seq. 2 Arch. f. Path. Anat. xxxix. 130, and elsewhere. * This Journal, in. '* Verhand. d. Heidelberg naturhist. nied. Verehis V. e. 1 Heft. v. ® Sitzimge b. d. Akad. d. Wise. 36. ® Digestion and Diet. 31—2
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