The Croonian lectures on the chemical side of nervous activity : delivered before the Royal College of Physicians of London, in June, 1901 / by W.D. Halliburton.

  • William Dobinson Halliburton
Date:
1901
Catalogue details

Licence: In copyright

Credit: The Croonian lectures on the chemical side of nervous activity : delivered before the Royal College of Physicians of London, in June, 1901 / by W.D. Halliburton. Source: Wellcome Collection.

Provider: This material has been provided by Royal College of Physicians, London. The original may be consulted at Royal College of Physicians, London.

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    TABLE XIV. Cats’ Sciatic Nerves. Weight in grammes of Yield in Phosphorus nerves taken grammes per cent. Animal Days after section of in Fresh Dry MgoPo07 dry tissue Cat 1 Normal l 1-793 0-620 0 026 1-16 Cat 2 ; 1 A. 2 ' I B. 3 3-297 1-007 0 035 0-97 P. 3 days, 20 hours ] 1 C. 4 1 I E. 5 1 h 3-594 1-1247 0-039 0-97 D. 6 j 1 R. 8 1-193 0-379 0 0078 0-57 N. 10 1-185 0-348 0 004 0-32 Q. 13 1-79 0-5145 0-005 0-27 J. 25 1-655 0-5315 traces 0. 27 1-215 0-338 traces W. 29 Right nerve'joined spon- 0-478 0-1314 0 0 taneously Left nerve sutured 0 502 0-1375 0 0 H. 44 1-272 0-348 0 0 S. 60 Left nerve not joined .. 0-505 0T39 0 0 Right nerve, regeneration 0-393 0-1075 0-0003 0-08 beginning I. 100 ]- 2-161 0-741 0 045 0-93 E 106 1 This table shows that in the early stages of degeneration the amount of phosphorus is not far removed from the normal. It is on the eighth day, when the Marchi reaction becomes well marked, that the first great drop in the percentage of phosphorus occurs. It continues to diminish and has practically disappeared by the twenty-fifth, and absolutely by the twenty-ninth day. With signs of commencing restoration of function it reappears, and is near the normal in the last two cats where regeneration had occurred. We have confined our observations to the peripheral parts of the nerves.9 9 Noll (loc. cii.) in some of his experiments examined the central stump of the divided nerve. He was able to perform some of his work on large animals (horses), and so could obtain sufficient material from the central end for analysis. Corresponding to what is termed “ disuse atrophy ” he found some diminution in the amount of protagon in this region, but the lessening was not so marked as in the peripheral end of the nerve. In the