History of cystic fibrosis / James M. Littlewood -- Epidemiology of cystic fibrosis / Sarah Walters and Anil Mehta -- Molecular biology of cystic fibrosis : CFTR processing and functions, and classes of mutations / Malka Nissim-Rafinia, Batsheva Kerem, and Eitan Kerem -- Pathophysiology : epithelial cell biology and ion channel function in the lung, sweat gland, and pancreas / Raymond D. Coakley and Richard C. Boucher -- Immunology of cystic fibrosis / Gerd Döring and Felix Ratjen -- Genotype-phenotype correlations and modifier genes / Jane C. Davies -- Variability of clinical course in cystic fibrosis / Michael Schechter -- Diagnosis of cystic fibrosis / Colin Wallis -- The challenge of screening newborn infants for cystic fibrosis / Kevin W. Southern -- How to manage the screened patient / Philip Robinson -- Microbiology of cystic fibrosis : role of the clinical microbiology laboratory, susceptibility and synergy studies, and infection control / Samiya Razvi and Lisa Saiman -- Respiratory disease : infection / Ian M. Balfour-Lynn and J. Stuart Elborn -- Respiratory disease : non-infectious complications / Margaret Hodson and Andrew Bush -- Sleep, lung mechanics, and work of breathing, including NIPPV / Brigitte Fauroux and Annick Clément -- Delivery of therapy to the cystic fibrosis lung / Harm A.W.M. Tiddens and Sunalene G. Devadason -- The upper airway in cystic fibrosis / William E. Grant -- Gastrointestinal disease in cystic fibrosis / Ian Gooding and David Westaby -- Liver, biliary, and pancreatic disease / Vicky Dondos and David Westaby -- Insulin deficiency and diabetes related to cystic fibrosis / Christopher D. Sheldon and Lee Dobson -- Growth and puberty / Nicola Bridges -- Cystic-fibrosis-related low bone mineral density / Sarah L. Elkin and Charles S. Haworth -- Other system disorders in cystic fibrosis / Khin Ma Gyi -- Sexual and reproductive health / Susan M. Sawyer -- Transplantation / Paul Aurora, Khin Gyi, and Martin Carby -- Using databases to improve care / Sheila G. McKenzie and Margaret E. Hodson -- Infant and pre-school children : lung function / Sarath Ranganathan -- Infant and pre-school children : role of bronchoscopy / Gary Connett -- Infant and pre-school children : imaging the lungs / Samatha Sonnappa and Catherine M. Owens -- Physiological monitoring of older children and adults / Mark Rosenthal -- Exercise : testing / David M. Orenstein and Wolfgang Gruber -- Exercise : use in therapy / David M. Orenstein and Linda W. Higgins -- Clinical outcome measures to assess new treatments for CF lung disease / Jane C. Davies and Eric W.F.W. Alton on behalf of the UKCF Gene Therapy Consortium -- Cystic fibrosis center care / Penny Agent and Susan Madge -- Nursing care / Susan Madge and Christine Hockings -- Physiotherapy / Craig Lapin, Anne Lapin, and Jennifer A. Pryor -- Nutritional aspects / Sue Wolfe and Sarah Collins -- Psychological aspects of cystic fibrosis / Alistair J.A. Duff and Helen Oxley -- Palliative care in cystic fibrosis / Catherine E. Urch and Margaret E. Hodson -- Gene and stem cell therapy / Uta Griesenbach and Eric W.F.W. Alton on behalf of the UKCF Gene Therapy Consortium -- Non-gene therapy treatments : what will they deliver? / Adam Jaffé and Pierre Barker -- The future : how will management change? / Andrew Bush and Duncan Geddes -- Transition form / Susan Madge and Jacqueline Francis -- Practical nursing care required by the cystic fibrosis patient and its delivery / Frances Duncan-Skingle and Tracey Catling.