A clinical study on primary carcinomatous and sarcomatous neoplasms between the folds of the broad ligaments : with a report of cases / by J.E. Janvrin.

  • Janvrin, J. E. (Joseph Edward), 1839-1911.
Date:
1891
Catalogue details

Licence: Public Domain Mark

Credit: A clinical study on primary carcinomatous and sarcomatous neoplasms between the folds of the broad ligaments : with a report of cases / by J.E. Janvrin. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    tlie changes in the organ of Rosenmiiller, unquestionably stamp a portion of the neoplasm as carcinomatous in character, which, in the absence of a similar growth in any other part of the body, must have originated in the epithelial structures in the parova- rium as a cylindrical-celled epithelial carcinoma. “ Although the larger pa,rt of the section resembled an adenoid hypertrophy, there was a point which was distinctly carcinoma- tous in character, otherwise this carcinomatous infiltration of the lymphatics would not have been developed. “ The remaining portions, which formed the larger part of the neoplasm, were distinctly composed of the connective-tissue type of formations, largely embryonic in character, and strongly resem- bled that class of growths commonly described as sarcomata. But the irregularity and complexity of its formation showed at once that it should not be classed among the true sarcomata. “ This prolific connective-tissue formation can be explained by a disturbance in the circulation and in the distribution of the nutritive supply, brought about in part by the local irritation of the carcinomatous grow.th, and possibly quite largely by the elec- trical treatment. (Signed) William H. Porter, M.D.” Case III. Oystic angiosarcoma of the left broad ligament; lipoma of the right; dilated tubes.—Mrs. E. M., aged twenty- eight years, three children; only the last one now living, eigh- teen months old. Was examined at my office May 8, 1891, and gave the following history: Has always been well until the be- ginning of the year 1891, then began to lose strength and ex- perienced more or less pain in region of both ovaries, especially the left. Has menstruated regularly about the middle of each month, and with no especial trouble uutil that of March, 1891, which came on (on tlie 17th) more freely than usual and with a good deal of pain. It continued profusely for three days and then began to check, but continued as a metrorrhagia for over two weeks. Again, on A])ril 15tli, it occurred, the How being profuse, and the pain, especially of the left side, being severe. It had continued every day since that date. Patient anajmic, pulse weak, and heart’s action somewhat irregular, with a harsh systolic murmur. Examination revealed an enlargement of the size of