Exophthalmic goître as a sequel of influenza : strophanthus as a remedy, and the effect of overdoses of thyreoid extract.
- McAdam, R.L.
- Date:
- 1894
Licence: Public Domain Mark
Credit: Exophthalmic goître as a sequel of influenza : strophanthus as a remedy, and the effect of overdoses of thyreoid extract. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
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Turn Tin Eonra o* •• BRAIN ” [\\ ZOtWelbeck Street, IPi s c £ 11 a n r . Exophthalmic Goitre as a Sequel of Influenza: Stro- phanthus as a Remedy; and the Effects of Overdoses of Thyreoid Extract.—At a meeting of the Victorian Branch of the British Medical Association held on November 15, 1893, Dr. R. L. McAdam read a paper in which he gave the history of a case of exophthalmic goitre that had seemed to be the sequel of an attack of influenza in a girl sixteen years old. A report of the proceedings is given in the December number of the Australian Medical Journal. For several months treat- ment of the exophthalmia was unsatisfactory, and in a consulta- tion it was suggested that one of the tonsils, which was un- healthy, be removed, and that was done. Dr. McAdam con- tinued as follows: “I saw no more of the patient till over two months had elapsed. Then, about the middle of March, she returned to her home, and once more put herself under my care. The effect of the treatment hitherto pursued had been disappointing, and almost nil. Practically, the status quo ante was still main- tained, though she complained now of palpitation, and I found a well-marked systolic apical murmur present. I determined to make yet another alteration in the treatment, and, while still continuing the faradism, I began to give her tincture of stro- plianthus. The preparation used was Burroughs, Wellcome & Co.’s, made according to Professor Frazer’s formula. The initial dose was tt],v in water three times a day. By gradual increments, I got the dose up to Tflxv thrice daily. This quan- tity she continued to take for many months, without the slightest appearance of toxic symptoms. Within two weeks after commencing the use of the strophanthus a chauge for the better became manifest; the rapidity of cardiac action lessened, the prominent eyeballs retreated, the thyreoid decreased in size, the tremors diminished, sleep became natural, appetite im- proved, the patient felt able for more exercise, she began to put on flesh, in fact, a general amelioration of her condition was unmistakably evident. In three months she increased two stone in weight. Toward the end of April, however, she be- came anaemic, and I gave her Blaud’s pills in conjunction with the strophanthus, with satisfactory results. As time rolled on, the patient steadily improved, and in July menstruation recom- menced, after a cessation of eight months. On several occa- sions I caused the strophanthus to be discontinued for a little while, and each time the old troubles began to reappear, to subside, however, on resuming the drug. Finally, in November last, I felt justified in pronouncing the patient cured. At that time she was in first-rate health; she could play tennis, take long walks, enjoy dancing, and, iD fact, engage in all the exer- cises to which she had formerly been accustomed. In October](https://iiif.wellcomecollection.org/image/b22325311_0004.jp2/full/800%2C/0/default.jpg)
