The essentials of materia medica and therapeutics / by Alfred Baring Garrod.

  • Garrod, Alfred Baring, 1819-1907.
Date:
1877
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Licence: Public Domain Mark

Credit: The essentials of materia medica and therapeutics / by Alfred Baring Garrod. Source: Wellcome Collection.

    497/560 (page 461)
    ^Ci r ?^!y^rt! i itife j k*s** ^T Wealii,’ v^lt, . i tb« fora of ' ?**«• *• lpMm IT* “•n u {nvr^att^i. ibliitfr liquid). *• ^antharidine. ■«'#i. Glacikl acetic icid. i. J. /teMnfo, CtotonovL T»rtantM sMinimr, ]■ ,nt ii applied to the skin, t the character of the effect: i; if the action is greater, iie beinj sei«rateil, by ^ueskinbeingmoredeeply Some of the sutetancrf lu,-e more than one °t th^ ' i- \-err diluted state, »«>*■%&,* zf-st ’. if anv »*'“ . ‘, J;1® jrbjf, 'V THERAPEUTICS. 461 fluid from the vessels of the affected part or its neighbourhood ; this effect is often of much value, and far above that of mere counter-irritation. 3. The pustulants induce a still deeper action, and are some- times of greater value than vesicants, especially in the treatment of deep-seated and chronic affections. 4. Many of the irritants are used for their direct effect on diseased parts, as in skin affections of various kinds ; and some of them, as the mercurial and iodine preparations, probably induce a specific effect as well as mere local irritation. Order 2.—External or Local Sedatives. External sedatives are substances which produce a direct seda- tive effect upon the part to which they are applied ; some, the local anaesthetics, causing complete loss of sensibility. Hydrocyanic acid. Belladonna. Atropia. Opium. Morphia salts. Solution of subacetate of lead. Acetate of lead. Subnitrate of bismuth. Creasote. Carbolic acid. Local anccslhelics. Ether spray. Ice. Bisulphide of carbon. Aconite. Aconitia. Yeratria. Effects of External Sedatives. Practically it may be said that all these substances act as sedatives upon the part to which they are applied, but in their mode of action they differ considerably • some, as hydrocyanic acid, aconite, and veratria, produce a direct sedative effect upon the nerves; some, as belladonna and atropia probably effect their object through the vessels. The local anaesthetics act, some by contracting the vessels and stopping for a while the circulation, thus producing a diminution or com° plete loss of the power of sensation of the parts to-which they are applied For the advantage of the ether spray, the profession is indebted to Dr. Richardson. p ession 18 Therapeutic Applications. These remedial agents are employed- 1. To relieve irritation and inflammatory action. 2. To allay neuralgic or other pain in the affected parts. 3. To f odi;ce a loss of sensation, and so allow operations to he