The coal-tar colors : with especial reference to their injurious qualities and the restriction of their use : a sanitary and medico-legal investigation / by Theodore Weyl ; with a preface by Professor Sell ; translated with permission of the author by Henry Leffman.
- Leffmann Henry, 1847-1930.
- Date:
- 1892
Licence: Public Domain Mark
Credit: The coal-tar colors : with especial reference to their injurious qualities and the restriction of their use : a sanitary and medico-legal investigation / by Theodore Weyl ; with a preface by Professor Sell ; translated with permission of the author by Henry Leffman. Source: Wellcome Collection.
Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.
119/180 page 117
![brown is one of the earliest-discovered azo-colors, but is still used to a large extent for the coloring of wool, leather, and jute. Cotton is dyed only after previous mordanting with tannin and tartar emetic. The specimens used in the experiment were from the Aniline Manufacturing Company of Berlin.* Exp. I.—Dog weighing 5690 grams, selected June nth, and on that and the following day showing no albumin in the urine. On June 13th, at 10.30 A. M., 2 grams were administered by the oesopha- geal tube. At 12 vomiting occurred. June 14th, 10 o'clock, 2 grams : vomiting at 12, no food taken. June 15th, no food taken, animal moved about a little. June i6th, 2 grams, two hours after which marked vomiting occurred. June 17th to 20th, no nourishment taken except water. June 21st, food taken, animal more lively, albumin in urine. June 22d, 5 grams, animal vomiting for one-half hour after administration. June 23d to 27th, almost no food taken, albumin in urine. June 28th, improving. June 30th, food taken, albumin in urine. Animal was under observation until July 15th. Finally only slight traces of albumin were detected in the urine and the appetite was restored. Exp. 2.—Dog weighing 29500 grams, selected April 29th, was found to have no albuminuria. On April 30th, received 5 grams by the oesophageal tube. May ist, urine brown, animal lively, appetite normal. May 2d, 5 grams by the tube. Bismarck brown was recog- nized in the urine by dyeing wool and chemical tests. May 4th, 5 grams administered. Urine brownish, no albumin. May 5th, urine normal, no color, no albumin. May 8th, 15 grams administered. Animal vomited once after the administration. May 12th, ate little, seemed sick. May 14th, seemed lively. May 15th, 15 grams given ; vomited after the administration. May i6th, no food taken, no albuminuria. May 18th, animal normal. May 22d, normal. Weight 2890Q grams. Exp. J.—Dog weighing 5500 grams, received during an entire month, daily, .25 gram of Bismarck brown with its food. The animal continued in good health during the entire time, did not vomit and ate as usual. It gained during the experiment about 350 grams. Exp. 4.—Dog weighing 6300 grams, received in the course of 20 [* I have found traces of copper in all the commercial samples of Bismarck brown I have tested.—Trans.]](https://iiif.wellcomecollection.org/image/b21700588_0119.jp2/full/800%2C/0/default.jpg)
